2-Chloromethyl-pyrrolidine hydrochloride

Base Information

• Chemical Name: 2-Chloromethyl-pyrrolidine hydrochloride
• CAS No.: 5044-50-8
• Molecular Formula: C₅H₁₀ClN*ClH
• Molecular Weight: 156.055
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID20544577
• Mol file: 5044-50-8.mol

Synonyms:2-Chloromethyl-pyrrolidine hydrochloride;5044-50-8;2-(Chloromethyl)pyrrolidine hydrochloride;2-(Chloromethyl)pyrrolidine HCl;2-(chloromethyl)pyrrolidine;hydrochloride;2-Chloromethyl-pyrrolidine HCl;SCHEMBL1656537;DTXSID20544577;MFCD15475012;AKOS024397780;SB32327;SB36773;SB37394;2-(Chloromethyl)pyrrolidinehydrochloride;AM100886;AS-42942;CS-0341886;EN300-215978;2-(Chloromethyl)pyrrolidine--hydrogen chloride (1/1)

Chemical Property of 2-Chloromethyl-pyrrolidine hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 2.10800
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 155.0268547
• Heavy Atom Count: 8
• Complexity: 56

Purity/Quality:

95% ^*data from raw suppliers

2-Chloromethyl-pyrrolidinehydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(NC1)CCl.Cl

Technology Process of 2-Chloromethyl-pyrrolidine hydrochloride

There total 1 articles about 2-Chloromethyl-pyrrolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxymethylpyrrolidine (498-63-5) → 2-pyrrolidinemethyl chloride hydrochloride (5044-50-8)

Guidance literature:

With hydrogenchloride; thionyl chloride;

Reference yield:

2-pyrrolidinemethyl chloride hydrochloride (5044-50-8) + 2-methyl-4-nitrophenyl isothiocyanate (135805-96-8) → 3-(2-methyl-4-nitrophenylimino)-2,5,6,7,7a-pentahydro-2-thiapyrrolizine

Guidance literature:

With 4-methyl-morpholine;

upstream raw materials:

2-hydroxymethylpyrrolidine

Refernces