1,4-Diazabicyclo[2.2.2]octane

Base Information Edit

Chemical Name:1,4-Diazabicyclo[2.2.2]octane
CAS No.:280-57-9
Deprecated CAS:101484-19-9,150605-01-9,203072-11-1,23790-33-2,88935-43-7,309955-09-7,165724-47-0,903524-95-8,746642-46-6,1357848-51-1,682335-96-2,2260745-52-4,150605-01-9,165724-47-0,203072-11-1,23790-33-2,309955-09-7,746642-46-6,88935-43-7
Molecular Formula:C6H12N2
Molecular Weight:112.175
Hs Code.:29335920
European Community (EC) Number:205-999-9
NSC Number:56362
UNII:X8M57R0JS5
DSSTox Substance ID:DTXSID0022016
Nikkaji Number:J5.451H
Wikipedia:DABCO
Wikidata:Q423673
Pharos Ligand ID:DLRGNCAASW1Z
Metabolomics Workbench ID:130613
ChEMBL ID:CHEMBL3183414
Mol file:280-57-9.mol

Synonyms:1,4-diazabicyclo(2.2.2)octane;1,4-diazabicyclo-octane;DABCO;DABCO cpd;triethylenediamine;triethylenediamine diacetate

Suppliers and Price of 1,4-Diazabicyclo[2.2.2]octane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,4-Diazabicyclo[2.2.2]octane
2.5g
$ 110.00

TCI Chemical
1,4-Diazabicyclo[2.2.2]octane >98.0%(GC)(T)
500g
$ 125.00

TCI Chemical
1,4-Diazabicyclo[2.2.2]octane >98.0%(GC)(T)
100g
$ 47.00

TCI Chemical
1,4-Diazabicyclo[2.2.2]octane >98.0%(GC)(T)
25g
$ 21.00

SynQuest Laboratories
1,4-Diazabicyclo[2.2.2]octane(DABCO)
500 g
$ 36.00

SynQuest Laboratories
1,4-Diazabicyclo[2.2.2]octane(DABCO)
100 g
$ 21.00

SynQuest Laboratories
1,4-Diazabicyclo[2.2.2]octane(DABCO)
1 kg
$ 61.00

Sigma-Aldrich
Dabco? 33-LV
100ml
$ 67.70

Sigma-Aldrich
1,4-Diazabicyclo[2.2.2]octane ReagentPlus , ≥99%
100g
$ 66.20

Sigma-Aldrich
1,4-Diazabicyclo[2.2.2]octane for synthesis. CAS 280-57-9, pH (H O, 20 °C) alkaline,Aqueous solution., for synthesis
8034560100
$ 58.30

Total 167 raw suppliers

Chemical Property of 1,4-Diazabicyclo[2.2.2]octane Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:2.9 mm Hg ( 50 °C)
Melting Point:156-159 °C(lit.)
Refractive Index:n20/D 1.4634(lit.)
Boiling Point:174 °C at 760 mmHg
PKA:3.0, 8.7(at 25℃)
Flash Point:62.2 °C
PSA：6.48000
Density:1.08 g/cm³
LogP:-0.50660
Storage Temp.:2-8°C
Sensitive.:Hygroscopic
Solubility.:400g/l
Water Solubility.:46 g/100 mL (26 ºC)
XLogP3:-0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:112.100048391
Heavy Atom Count:8
Complexity:61.5

Purity/Quality:

99% ^*data from raw suppliers

1,4-Diazabicyclo[2.2.2]octane ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, F
Hazard Codes:Xn,F
Statements: 22-36/37/38-52/53-41-36/38-11
Safety Statements: 26-60-37/39-3-16-36/37-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Amines, Cyclic
Canonical SMILES:C1CN2CCN1CC2
Recent ClinicalTrials:Long-term Safety and Efficacy Study of Teduglutide in Pediatric Participants With Short Bowel Syndrome (SBS)
Uses An anti-fade reagent shown to scavenge free-radicals due to flurochrome excitation. 1,4-Diazabicyclo[2.2.2]octane is used as polyurethane catalyst, Balis-Hillman reaction catalyst complexing ligand and lewis base. It finds use in dye lasers and in mounting samples for fluorescence microscopy and as anti-fade reagent shown to scavenge free radicals due to flurochrome excitation of fluorochromes. Further, it is an oxidation and polymerization catalyst.

Technology Process of 1,4-Diazabicyclo[2.2.2]octane

There total 64 articles about 1,4-Diazabicyclo[2.2.2]octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.6%

: C₆H₈N₂O₂

: 280-57-9,88935-43-7
1,4-diaza-bicyclo[2.2.2]octane

Guidance literature:: With Rh/Al₂O₃; hydrogen; In tetrahydrofuran; at 175 ℃; under 37503.8 Torr; Reagent/catalyst; Temperature; Solvent; Sealed tube;