1-(4-iodo-2-methylphenyl)ethanone

Base Information

• Chemical Name: 1-(4-iodo-2-methylphenyl)ethanone
• CAS No.: 52164-27-9
• Molecular Formula: C9H9IO
• Molecular Weight: 0.00000
• Mol file: 52164-27-9.mol

Synonyms:

Chemical Property of 1-(4-iodo-2-methylphenyl)ethanone

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

1-(4-iodo-2-methylphenyl)ethanone 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-iodo-2-methylphenyl)ethanone

There total 6 articles about 1-(4-iodo-2-methylphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.5%

3-Iodotoluene (625-95-6) + acetyl chloride (75-36-5) → 2-methyl-4-iodoacetophenone (52164-27-9) + 2’-iodo-4’-methylacetophenone (52107-83-2)

Guidance literature:

With aluminium trichloride; In 1,2-dichloro-ethane; 1.) room temp., 1 h, 2.) 50 deg C, 2 h;

DOI:10.1021/jo982392m

Reference yield:

3-Iodotoluene (625-95-6) + acetyl chloride (75-36-5) → 2-methyl-4-iodoacetophenone (52164-27-9)

Guidance literature:

With aluminium trichloride;

Reference yield:

→ 2-methyl-4-iodoacetophenone (52164-27-9)

Guidance literature:

With sulfuric acid; water; potassium iodide;

DOI:10.1246/bcsj.30.958

upstream raw materials:

2-methyl-4-iodobenzonitrile

3-Iodotoluene

acetyl chloride

4-amino-2-methylbenzonitrile

Downstream raw materials:

4-iodo-2-methylbenzoic acid

4-(2-{4-[4-(4-iodo-phenylethynyl)-3-methyl-phenylethynyl]-phenylsulfanyl}-ethyl)-pyridine

4-{4-[2-(tert-Butyl-dimethyl-silanyl)-ethylsulfanyl]-phenylethynyl}-2-methyl-1-trimethylsilanylethynyl-benzene

2-Methyl-4-[4-(2-trimethylsilanyl-ethylsulfanyl)-phenylethynyl]-1-trimethylsilanylethynyl-benzene

Refernces

• 1、 Yu,Chong, Yoochul,Kayyem, Jon Faiz,Gozin, Michael. "Soluble ferrocene conjugates for incorporation into self-assembled monolayers". . p. 2070 - 2079. Retrieved 2007/10/03.
• 2、 BUU-HOI,JACQUIGNON. "Observations made during the course of synthesis of iodine derivatives". . p. 786 - 788. Retrieved 2007/10/08.