P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE

Base Information

• Chemical Name: P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE
• CAS No.: 17691-02-0
• Molecular Formula: C18H27NO11
• Molecular Weight: 433.412
• Hs Code.: 29389090
• Mol file: 17691-02-0.mol

Synonyms:Glucopyranoside,p-aminophenyl 4-O-b-D-galactopyranosyl-, b-D- (8CI);Lactoside, p-aminophenyl (6CI,7CI);4-Aminophenyl b-D-lactopyranoside;p-Aminophenylb-lactoside;

Chemical Property of P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE

Chemical Property:

• Appearance/Colour: off-white crystalline solid
• Vapor Pressure: 3E-25mmHg at 25°C
• Melting Point: 200-204 °C
• Refractive Index: 1.675
• Boiling Point: 774.6 °C at 760 mmHg
• Flash Point: 422.3 °C
• PSA: 204.55000
• Density: 1.64g /cm³
• LogP: -3.14710
• Storage Temp.: -20°C Freezer
• Solubility.: Methanol (Slightly, Heated), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

p-Aminophenyl b-D-Lactopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A useful artificial carbohydrate protein conjugate, p-Aminophenyl β-D-lactopyranoside can be used as an antigen or immunogen

Technology Process of P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE

There total 12 articles about P-AMINOPHENYL BETA-D-LACTOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside (4419-94-7) → p-Aminophenyl 4-O-(β-D-galactopyranosyl)-β-D-glucopyranoside (17691-02-0)

Guidance literature:

With hydrogen; palladium dihydroxide; In water; at 20 ℃; for 15h; atmospheric pressure;

DOI:10.1016/j.tet.2005.03.102

Reference yield: 70.0%

p-nitrophenyl β-D-galactopyranosyl-(1->4)-β-D-galactopyranoside (196608-23-8) → p-Aminophenyl 4-O-(β-D-galactopyranosyl)-β-D-glucopyranoside (17691-02-0)

Guidance literature:

Reference yield:

p-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyde (5987-78-0) → p-Aminophenyl 4-O-(β-D-galactopyranosyl)-β-D-glucopyranoside (17691-02-0)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOMe / methanol

2: 0.87 g / acetic acid; H₂ / 10percent Pd/C / methanol; H₂O / 760.05 Torr

3: Agrobacterium sp ABG E₃₅₈S gomodenate / various solvent(s) / 17 h / Enzymatic reaction

With Agrobacterium sp ABG E₃₅₈S gomodenate; hydrogen; sodium methylate; acetic acid; 10percent Pd/C; In methanol; water; 1: Zemplen deacetylation;

DOI:10.1021/jo0163445

upstream raw materials:

4-nitrophenyl β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside

4-aminophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1→4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside

α-galactosyl fluoride

4-aminophenyl β-D-glucopyranoside

Downstream raw materials:

p-succinylamidophenyl β-lactoside

N-{4-[(2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-hydroxymethyl-5-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-phenyl}-acrylamide

Refernces

• 1、 -. "BEVERAGE DISPENSING EQUIPMENT". Paragraph 00154; 00157. . Retrieved 2016/12/01.
• 2、 Nishida, Yoshihiro,Tsurumi, Tomoaki,Sasaki, Kenji,Watanabe, Kenta,Dohi, Hirofumi,Kobayashi, Kazukiyo. "Design and Synthesis of C3-Symmetric LewisX Antigen". . p. 3775 - 3778. Retrieved 2007/10/03.