Sultopride hydrochloride

Base Information

• Chemical Name: Sultopride hydrochloride
• CAS No.: 55619-22-2
• Molecular Formula: C₁₇H₂₆N₂O₄S*ClH
• Molecular Weight: 390.931
• European Community (EC) Number: 259-726-3,245-829-0
• UNII: 8Q6926T32J
• DSSTox Substance ID: DTXSID0049070
• Wikidata: Q27270888
• ChEMBL ID: CHEMBL3182384
• Mol file: 55619-22-2.mol

Synonyms:4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide;amisulpride;Barnetil;DAN 2163;DAN-2163;LIN 1418;LIN-1418;N-(ethyl-1-pyrrolidinyl- 2-methyl)methoxy-2-ethylsulfonyl-5-benzamide;Solian;sultopride;sultopride hydrochloride

Chemical Property of Sultopride hydrochloride

Chemical Property:

• Boiling Point: 530°Cat760mmHg
• Flash Point: 274.3°C
• PSA: 84.09000
• Density: g/cm³
• LogP: 3.91450
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 390.1380062
• Heavy Atom Count: 25
• Complexity: 517

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)CC)OC.Cl

Technology Process of Sultopride hydrochloride

There total 2 articles about Sultopride hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

→ Sultopride hydrochloride (55619-22-2,23694-17-9)

Guidance literature:

Reference yield:

1-ethyl-2-pyrrolidinemethanamine (26116-12-1) + methyl 2-methoxy-5-(ethylsulfonyl)benzoate → Sultopride hydrochloride (55619-22-2,23694-17-9)

Guidance literature:

1-ethyl-2-pyrrolidinemethanamine; methyl 2-methoxy-5-(ethylsulfonyl)benzoate; In ethylene glycol; at 90 - 95 ℃; for 10h; Inert atmosphere;

With hydrogenchloride; In ethanol; water; Inert atmosphere; Reflux;

upstream raw materials:

1-ethyl-2-pyrrolidinemethanamine

Refernces

• 1、 -. "Processes of producing 2,5-disubstituted benzamides". . . Retrieved 2008/06/13.