4-Acryloylmorpholine

Base Information

• Chemical Name: 4-Acryloylmorpholine
• CAS No.: 5117-12-4
• Deprecated CAS: 136894-88-7
• Molecular Formula: C7H11 N O2
• Molecular Weight: 141.17
• Hs Code.: 2934999090
• European Community (EC) Number: 418-140-1,610-626-1
• NSC Number: 162221
• UNII: K0Y58P61JA
• DSSTox Substance ID: DTXSID0044947
• Nikkaji Number: J87.318G
• Wikidata: Q27281799
• ChEMBL ID: CHEMBL3187188
• Mol file: 5117-12-4.mol

Synonyms:4-acryloylmorpholine

Chemical Property of 4-Acryloylmorpholine

Chemical Property:

• Vapor Pressure: 4.95E-08mmHg at 25°C
• Melting Point: -35 ºC
• Refractive Index: n20/D 1.512(lit.)
• Boiling Point: 296.8 °C at 760 mmHg
• PKA: -1.08±0.20(Predicted)
• Flash Point: >110 ºC
• PSA: 29.54000
• Density: 1.122
• LogP: -0.03090
• Storage Temp.: 2-8°C
• Sensitive.: Light Sensitive
• Solubility.: Soluble in water
• Water Solubility.: 1000g/L at 20℃
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 141.078978594
• Heavy Atom Count: 10
• Complexity: 139

Purity/Quality:

99% ^*data from raw suppliers

4-Acryloylmorpholine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41-43-48/22
• Safety Statements: 23-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC(=O)N1CCOCC1
• Uses: 4-Acryloylmorpholine is used in adhesives, UV curable resins, industrial coatings, UV printing ink, oil recovery polymer, medicinal and commodity chemicals.

Technology Process of 4-Acryloylmorpholine

There total 41 articles about 4-Acryloylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C11H21NO3 → N-Acryloylmorpholine (5117-12-4,28902-82-1)

Guidance literature:

With 10H-phenothiazine; sodium methylate; In glycerol; at 200 ℃; Pyrolysis;

Reference yield: 96.1%

2-hydroxy-1-(morpholin-4-yl)-1-propanone (27097-66-1) → N-Acryloylmorpholine (5117-12-4,28902-82-1)

Guidance literature:

With sulfuric acid; acetic anhydride; at 550 ℃; Temperature;

Reference yield: 96.0%

4-(3-methoxy-propionyl)-morpholine (860248-52-8) → N-Acryloylmorpholine (5117-12-4,28902-82-1)

Guidance literature:

With sodium methylate; 4-methoxy-phenol; at 200 ℃; Pyrolysis;

upstream raw materials:

morpholine

acryloyl chloride

4-(3-methoxy-propionyl)-morpholine

morpholin hydrochloride

Downstream raw materials:

diethyl ((2S,4S,5S)-4-(morpholine-4-carbonyl)-5-phenylpyrrolidine-2-yl)phosphonate

(E)-2-(3-morpholino-3-oxoprop-1-en-1-yl)benzaldehyde

C₂₉H₂₇N₃O₂

N-morpholinocinnamide

Refernces

• 1、 -. "Method for catalytically synthesizing acrylamide compound by MOFs-derived zirconium-based ternary oxide solid acid". Paragraph 0063-0064. . Retrieved 2021/11/14.
• 2、 -. "Synthesis method of 4-acryloylmorpholine". Paragraph 0021-0026. . Retrieved 2021/06/26.