Technology Process of 2,3-Bis(2-fluoro-4-hydroxyphenyl)-2,3-dimethylbutane
There total 3 articles about 2,3-Bis(2-fluoro-4-hydroxyphenyl)-2,3-dimethylbutane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; sodium hydroxide; boron tribromide;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) Mg / 1.) ether, reflux, 0.5 h, 2.) ether, reflux, 2 h
2: 40 percent / TiCl3, LiAlH4 / 1,2-dimethoxy-ethane / 16 h / Heating
3: 1.) BBr3, 2.) 2N NaOH / 1.) CH2Cl2, RT, 4 h, 2.) CH2Cl2, MeOH
With
sodium hydroxide; lithium aluminium tetrahydride; titanium(III) chloride; boron tribromide; magnesium;
In
1,2-dimethoxyethane;
DOI:10.1021/jm00147a031
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 40 percent / TiCl3, LiAlH4 / 1,2-dimethoxy-ethane / 16 h / Heating
2: 1.) BBr3, 2.) 2N NaOH / 1.) CH2Cl2, RT, 4 h, 2.) CH2Cl2, MeOH
With
sodium hydroxide; lithium aluminium tetrahydride; titanium(III) chloride; boron tribromide;
In
1,2-dimethoxyethane;
DOI:10.1021/jm00147a031
