Glycine, N-(phosphonomethyl)-, 1-methyl ester

Base Information

• Chemical Name: Glycine, N-(phosphonomethyl)-, 1-methyl ester
• CAS No.: 39600-44-7
• Molecular Formula: C4H10 N O5 P
• Molecular Weight: 183.101
• Hs Code.: 2931900090
• ChEMBL ID: CHEMBL98618
• DSSTox Substance ID: DTXSID80192715
• Wikidata: Q83065377
• Mol file: 39600-44-7.mol

Synonyms:39600-44-7;CHEMBL98618;Glycine, N-(phosphonomethyl)-, 1-methyl ester;[(2-METHOXY-2-OXOETHYL)AMINO]METHYLPHOSPHONIC ACID;N-(methoxcarbonylmethyl)aminomethylphosphonic acid (Glyphosate methyl ester);(((2-Methoxy-2-oxoethyl)amino)methyl)phosphonic acid;{[(2-methoxy-2-oxoethyl)amino]methyl}phosphonic acid;SCHEMBL2988907;DTXSID80192715;BDBM50281351;MFCD16876768;AKOS017343544;(Phosphonomethyl-amino)-acetic acid methyl ester;EN300-7699776;[(2-methoxy-2-oxo-ethyl)amino]methylphosphonic acid

Chemical Property of Glycine, N-(phosphonomethyl)-, 1-methyl ester

Chemical Property:

• PSA: 105.67000
• LogP: -0.72490
• XLogP3: -4.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 183.02965942
• Heavy Atom Count: 11
• Complexity: 175

Purity/Quality:

99% ^*data from raw suppliers

N-(METHOXCARBONYLMETHYL)AMINOMETHYL PHOSPHONIC ACID (GLYPHOSATE METHYL ESTER) 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)CNCP(=O)(O)O

Technology Process of Glycine, N-(phosphonomethyl)-, 1-methyl ester

There total 4 articles about Glycine, N-(phosphonomethyl)-, 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methanol (67-56-1) + N-(phosphonemethyl)glycine (1071-83-6) → methyl N-phosphonomethylglycinate (39600-44-7)

Guidance literature:

methanol; N-(phosphonemethyl)glycine; With hydrogenchloride; at 40 ℃; for 2h;

With oxirane; at 20 ℃;

Reference yield:

N-(phosphonemethyl)glycine (1071-83-6) → methyl N-phosphonomethylglycinate (39600-44-7)

Guidance literature:

With triethylamine; In methanol;

Reference yield:

[(Diethoxy-phosphorylmethyl)-amino]-acetic acid methyl ester → methyl N-phosphonomethylglycinate (39600-44-7)

Guidance literature:

With trimethylsilyl bromide; water; Yield given. Multistep reaction; 1.) 0 deg C, then 10 h, room t., 2.) 20 min;

DOI:10.1021/ja00256a033

upstream raw materials:

N-(phosphonemethyl)glycine

methanol

Downstream raw materials:

glyphosate amide

N-phosphonomethylglycine 2-methyl-2-phenyl hydrazide

N-(phosphonemethyl)glycine

Refernces

• 1、 -. "OPTICAL ISOMER OF R-FORM OF DIPHENYL ETHER DERIVATIVE AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT". . . Retrieved 2008/06/13.
• 2、 -. "Increasing carbohydrate deposition in plants with N-phosphono-methylglycine and derivatives thereof". . . Retrieved 2008/06/13.