Fluocoutolone Hexanoate

Base Information

• Chemical Name: Fluocoutolone Hexanoate
• CAS No.: 303-40-2
• Molecular Formula: C₂₈H₃₉FO₅
• Molecular Weight: 474.613
• Mol file: 303-40-2.mol

Synonyms:Pregna-1,4-diene-3,20-dione,6a-fluoro-11b,21-dihydroxy-16a-methyl-, 21-hexanoate (7CI,8CI);Hexanoic acid, 21-ester with 6a-fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione(8CI); 6a-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione21-hexanoate; 6a-Fluoro-11b-hydroxy-21-hexanoyloxy-16a-methylpregna-1,4-diene-3,20-dione;Ficoid; Fluocortolone 21-hexanoate; Fluocortolone caproate; Fluocortolonehexanoate; Fluorocortolone 21-caproate; SH 770

Chemical Property of Fluocoutolone Hexanoate

Chemical Property:

• Vapor Pressure: 1.95E-16mmHg at 25°C
• Melting Point: 242-245°
• Boiling Point: 591.1°Cat760mmHg
• PKA: 14.05±0.70(Predicted)
• Flash Point: 311.3°C
• PSA: 80.67000
• Density: 1.17g/cm³
• LogP: 4.76790
• Storage Temp.: -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fluocortolone21-Hexanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Glucocorticoid.

Technology Process of Fluocoutolone Hexanoate

There total 2 articles about Fluocoutolone Hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6α-Fluor-11β-hydroxy-21-hexanoyloxy-16α-methyl-1,4-pregnadien-3,20-dion (303-40-2,25091-93-4)

Guidance literature:

entspr. 6α-Fluor-9α-chlor-pregnadien, Tributylzinnhydrid;

Reference yield:

→ Hexanoic acid 2-((6S,10R,11R,13S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester (303-40-2,25091-93-4)

Guidance literature:

Alkohol I (R=H), (C5H11CO)2O;