2-Cyclopropene-1-thione, 2-methyl-3-phenyl-

Base Information

• Chemical Name: 2-Cyclopropene-1-thione, 2-methyl-3-phenyl-
• CAS No.: 56764-07-9
• Molecular Formula: C10H8S
• Molecular Weight: 160.24
• Mol file: 56764-07-9.mol

Synonyms:

Chemical Property of 2-Cyclopropene-1-thione, 2-methyl-3-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Cyclopropene-1-thione, 2-methyl-3-phenyl-

There total 2 articles about 2-Cyclopropene-1-thione, 2-methyl-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-methyl-3-phenylcyclopropenone (26307-30-2) → methylphenylcyclopropenethione (56764-07-9)

Guidance literature:

With Lawessons reagent; In dichloromethane; at 23 ℃;

DOI:10.1021/acs.orglett.8b02296

Reference yield: 89.0%

C12H11OS(1+)*ClO4(1-) → methylphenylcyclopropenethione (56764-07-9)

Guidance literature:

With hydrogenchloride; In dichloromethane; for 0.5h;

DOI:10.1246/bcsj.55.1973

Reference yield: 80.0%

methylphenylcyclopropenethione (56764-07-9) → 4-methyl-5-phenyl-1,2-dithiole-3-thione (10269-25-7)

Guidance literature:

With sulfur; potassium fluoride; In N,N-dimethyl-formamide; at 20 ℃; for 12h; regioselective reaction; Schlenk technique;

DOI:10.1021/acs.orglett.0c01914

upstream raw materials:

2-methyl-3-phenylcyclopropenone

Downstream raw materials:

methyl 3-methoxy-2-phenyl-2-butenethioate

methyl 2-phenyl-3-oxobutanethioate

2-methyl-3-phenylcyclopropenone

4-methyl-5-phenyl-1,2-dithiole-3-thione

Refernces

• 1、 Zhao, Wen-Tao,Shi, Min. "Reactions of cyclopropenethiones and acetylenedicarboxylates: Synthesis of substituted thioethers and thiocyclobutanones". supporting information. p. 5086 - 5089. Retrieved 2015/08/06.
• 2、 Yoshida, Hiroshi,Nakajima, Mikito,Ogata, Tsuyoshi. "Synthesis of Cyclopropenethiones or 3,3-Biscyclopropenes from Cyclopropenones and Thiocarboxylic Acids". . p. 36 - 38. Retrieved 2007/10/02.