1,3-Propanediol, 2,2-bis(hydroxymethyl)-, 1-nitrate

Base Information

• Chemical Name: 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, 1-nitrate
• CAS No.: 1607-00-7
• Molecular Formula: C5H11 N O6
• Molecular Weight: 181.145
• Hs Code.: 2920909090
• Mol file: 1607-00-7.mol

Synonyms:Pentaerythritol,mononitrate (8CI); Pentaerythritol, nitrate (7CI); Pentaerythrityl mononitrate

Chemical Property of 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, 1-nitrate

Chemical Property:

• Vapor Pressure: 0.000122mmHg at 25°C
• Boiling Point: 299.1°Cat760mmHg
• Flash Point: 134.7°C
• PSA: 115.74000
• Density: 1.475g/cm³
• LogP: -1.31880

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, 1-nitrate

There total 6 articles about 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, 1-nitrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

Pentaerythritol (115-77-5) → pentaerythrityl mononitrate (1607-00-7) + 2,2-bis(hydroxymethyl)propane-1,3-diol dinitrate (1607-01-8)

Guidance literature:

With nitric acid; In water; 1,2-dichloro-ethane; at 5 ℃; for 1h;

DOI:10.1023/A:1026085511220

Reference yield: 40.2%

2-(bromomethyl)-2-(hydroxymethyl)propane-1,3-diol (19184-65-7) → pentaerythrityl mononitrate (1607-00-7)

Guidance literature:

With silver nitrate; In acetonitrile; at 70 ℃; for 24h; Darkness;

Reference yield:

Pentaerythritol tetranitrate (78-11-5) → pentaerythrityl mononitrate (1607-00-7)

Guidance literature:

With hydrazine hydrate; In 1,4-dioxane; ethanol; for 2.5h; Heating;

upstream raw materials:

Pentaerythritol tetranitrate

2,2-bis(hydroxymethyl)propane-1,3-diol dinitrate

Pentaerythritol

2-(bromomethyl)-2-(hydroxymethyl)propane-1,3-diol

Downstream raw materials:

3,3-bis(hydroxymethyl)oxetane

2-(Hydroxymethyl)allyl alcohol

3,3-bis(nitratomethyl)oxetane

Refernces

• 1、 -. "Method for preparing nitro compound by using graphene to catalyze nitric oxide". Paragraph 0031; 0032. . Retrieved 2018/06/16.
• 2、 Lange, Kathrin,Koenig, Andreas,Roegler, Carolin,Seeling, Andreas,Lehmann, Jochen. "NO donors. Part 18: Bioactive metabolites of GTN and PETN-Synthesis and vasorelaxant properties". experimental part. p. 3141 - 3144. Retrieved 2010/01/17.