(4-Bromophenyl)diphenylphosphine oxide

Base Information

• Chemical Name: (4-Bromophenyl)diphenylphosphine oxide
• CAS No.: 5525-40-6
• Molecular Formula: C21H17NO
• Molecular Weight: 357.186
• European Community (EC) Number: 834-602-7
• Nikkaji Number: J1.402.782C
• Mol file: 5525-40-6.mol

Synonyms:(4-Bromophenyl)diphenylphosphine oxide;5525-40-6;1-bromo-4-(diphenylphosphoroso)benzene;1-bromo-4-diphenylphosphorylbenzene;(4-Bromophenyl)diphenylphosphineoxide;MFCD00411450;Phosphine oxide, (4-bromophenyl)diphenyl-;C18H14BrOP;SCHEMBL6568180;PCYBTUUJXASDIX-UHFFFAOYSA-N;p-Bromophenyldiphenylphosphine oxide;4-bromophenyldiphenylphosphine oxide;p-bromophenyl-diphenyl-phosphine oxide;AKOS028114091;AS-63500;SY234348;B5459;CS-0040658;C75588;A847515

Chemical Property of (4-Bromophenyl)diphenylphosphine oxide

Chemical Property:

• Vapor Pressure: 3.66E-10mmHg at 25°C
• Melting Point: 153.0 to 157.0 °C
• Boiling Point: 500.9°Cat760mmHg
• Flash Point: 257.9°C
• PSA: 29.96000
• Density: 1.166g/cm³
• LogP: 4.93460
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 355.99656
• Heavy Atom Count: 21
• Complexity: 341

Purity/Quality:

98% ^*data from raw suppliers

(4-Bromophenyl)diphenylphosphine Oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC=C(C=C3)Br

Technology Process of (4-Bromophenyl)diphenylphosphine oxide

There total 13 articles about (4-Bromophenyl)diphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(4-bromophenyl)diphenylphosphane (734-59-8) → (4-bromophenyl)diphenylphosphine oxide (5525-40-6)

Guidance literature:

With dihydrogen peroxide; In dichloromethane; at 0 ℃;

DOI:10.1021/jacs.7b12251

Reference yield: 95.0%

bis(4-bromophenyl)iodonium triflate (139139-81-4) + Diphenylphosphine oxide (4559-70-0) → (4-bromophenyl)diphenylphosphine oxide (5525-40-6)

Guidance literature:

With triethylamine; copper(l) chloride; In dichloromethane; at 20 ℃; for 0.166667h; Schlenk technique;

DOI:10.1021/jo4012199

Reference yield: 93.0%

1,4-bromoiodobenzene (589-87-7) + Diphenylphosphine oxide (4559-70-0) → (4-bromophenyl)diphenylphosphine oxide (5525-40-6)

Guidance literature:

With triethylamine; for 3h; Reflux;

DOI:10.1002/aoc.6480

upstream raw materials:

1,4-bromoiodobenzene

triphenylphosphine

1.4-dibromobenzene

Diphenylphosphinic chloride

Downstream raw materials:

(4-methoxycarbonylphenyl)diphenylphosphine oxide

1-(4-(diphenylphosphoryl)phenyl)ethan-1-one

2-[(4-diphenylphosphoryl)phenyl]pyridine

Refernces

• 1、 Szalontai,Szabó,Besenyei. "A new heterotopic Ar-BIAN ligand with a pendant P donor site". . p. 156 - 165. Retrieved 2015.
• 2、 Chen, Yu-Xuan,Zhang, Shuo,Xue, Yu-Jie,Mo, Li-Ping,Zhang, Zhan-Hui. "Palladium anchored on a covalent organic framework as a heterogeneous catalyst for phosphorylation of aryl bromides". . . Retrieved 2021/11/05.
• 3、 -. "Aggregation-induced light emission material and preparation method thereof". Paragraph 0016-0018. . Retrieved 2021/09/22.