CID 6507255

Base Information

• Chemical Name: CID 6507255
• CAS No.: 289893-25-0
• Molecular Formula: C14H20 Cl N3 O3
• Molecular Weight: 313.784
• NCI Thesaurus Code: C79744
• Nikkaji Number: J2.650.951C
• Wikipedia: Arimoclomol
• Mol file: 289893-25-0.mol

Synonyms:arimoclomol;BRX-220;BRX220

Chemical Property of CID 6507255

Chemical Property:

• Vapor Pressure: 1.85E-12mmHg at 25°C
• Melting Point: 93 - 95o C
• Boiling Point: 539.2°Cat760mmHg
• PKA: 14.03±0.20(Predicted)
• Flash Point: 279.9°C
• PSA: 71.36000
• Density: 1.32g/cm³
• LogP: 1.53140
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 313.1193192
• Heavy Atom Count: 21
• Complexity: 337

Purity/Quality:

99%, ^*data from raw suppliers

Arimoclomol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CC(CON=C(C2=C[N+](=CC=C2)[O-])Cl)O
• Isomeric SMILES: C1CCN(CC1)C[C@H](CO/N=C(\C2=C[N+](=CC=C2)[O-])/Cl)O
• Recent ClinicalTrials: Early Access Program With Arimoclomol in US Patients With NPC
• Recent EU Clinical Trials: An open-label, non-randomized trial to investigate the efficacy and safety of early versus delayed start of arimoclomol in patients with sporadic inclusion body myositis who have completed the IBM4809 trial.
• Uses: Arimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.

Technology Process of CID 6507255

There total 1 articles about CID 6507255 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ arimoclomol (289893-25-0)

Guidance literature:

Refernces