Paniculidine C

Base Information

• Chemical Name: Paniculidine C
• CAS No.: 97399-95-6
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.284
• Mol file: 97399-95-6.mol

Synonyms:(1αS, 6αR)-1α-(Hydroxymethyl)-5-(4-methylpent-3-en-1-yl)-1α, 2, 2α, 6α-tetrahydrooxireno[f][1]benzofuran-4, 6-dione;

Chemical Property of Paniculidine C

Chemical Property:

• Boiling Point: 489.9 °C at 760 mmHg
• Flash Point: 185.5 °C
• PSA: 36.02000
• Density: 1.31 g/cm³
• LogP: 2.72890

Purity/Quality:

98%min ^*data from raw suppliers

PaniculidineC ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Paniculidine C

There total 10 articles about Paniculidine C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(R)-3-<4-(2-tetrahydropyranyloxy)-3-methylbutyl>indole (129112-07-8) → (R)-paniculidinol (97399-95-6)

Guidance literature:

With pyridinium p-toluenesulfonate; In ethanol; at 50 - 60 ℃; for 3h;

Reference yield:

paniculidine E → (R)-paniculidinol (97399-95-6) + 2-methyl-4-(3-indolyl)butyric acid

Guidance literature:

paniculidine E; With potassium carbonate; In methanol; at 80 ℃; for 4h;

With hydrogenchloride; In methanol; water;

DOI:10.1080/10286020.2017.1327950

Reference yield:

paniculidine B (97399-94-5) → (R)-paniculidinol (97399-95-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 3h;

DOI:10.1016/0031-9422(89)85027-7

upstream raw materials:

(R)-3-<4-(2-tetrahydropyranyloxy)-3-methylbutyl>indole

paniculidine B

paniculidine A

(R)-2-methylbut-3-en-1-ol

Refernces

• 1、 Cheskis, B. A.,Alekseev, I. G.,Moiseenkov, A. M.. "SYNTHESIS OF THE (S)-ENANTIOMER OF PANICULIDINE A. ABSOLUTE CONFIGURATION OF NATURAL PANICULIDINES". . p. 364 - 369. Retrieved 2007/10/02.
• 2、 Kinoshita,Tatara,Sankawa. "Structures of paniculidines A and B: novel prenylindoles from Murraya paniculata". . p. 1770 - 1773. Retrieved 2007/10/02.