Terpenes andTerpenoids, limonene fraction

Base Information

• Chemical Name: Terpenes andTerpenoids, limonene fraction
• CAS No.: 65996-98-7
• Molecular Formula: C₁₂H₁₀N₂O
• Molecular Weight: 198.224
• Mol file: 65996-98-7.mol

Synonyms:

Chemical Property of Terpenes andTerpenoids, limonene fraction

Chemical Property:

• Boiling Point: 175.4°Cat760mmHg
• Flash Point: 42.8°C
• Density: 0.834g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Terpenes andTerpenoids, limonene fraction

There total 42 articles about Terpenes andTerpenoids, limonene fraction which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-iodopyridine (1120-90-7) + carbon monoxide (201230-82-2) + aniline (62-53-3) → N-phenylnicotinamide (1752-96-1)

Guidance literature:

With potassium phosphate; Pd((imidazolium)acetonaphthene)(allyl)Cl; In toluene; at 90 ℃; for 19h; under 760.051 Torr; Schlenk technique;

DOI:10.1021/ol401550h

Reference yield: 94.0%

3-Chloropyridine (626-60-8) + carbon monoxide (201230-82-2) + aniline (62-53-3) → N-phenylnicotinamide (1752-96-1)

Guidance literature:

With 4 A molecular sieve; sodium phenoxide; palladium diacetate; In dimethyl sulfoxide; at 100 ℃; for 15h; under 760.051 Torr;

DOI:10.1002/anie.200702943

Reference yield: 93.0%

iodobenzene (591-50-4) + nicotinamide (98-92-0,1255150-40-3) + cyclohexylamine (108-91-8,157973-60-9) → N-phenylnicotinamide (1752-96-1) + N-phenyl-2-cyclohexylamine (1821-36-9)

Guidance literature:

With copper(l) iodide; cesium fluoride; In dimethyl sulfoxide; at 130 ℃; for 24h; Inert atmosphere; Glovebox;

DOI:10.1002/ejoc.201400033

upstream raw materials:

nicotinic acid

N,N'-diphenylsulfamide

2,4-bis(anilino)-1,3-diphenyl-1,3,2,4-diazadiphosphetidine

aniline

Refernces

• 1、 Zhao, Rong,Dong, Wenwen,Teng, Jiangge,Wang, Zhiwei,Wang, Yunzhong,Yang, Jianguo,Jia, Qiang,Chu, Changhu. "Activated charcoal supported copper nanoparticles: A readily available and inexpensive heterogeneous catalyst for the N-arylation of primary amides and lactams with aryl iodides". supporting information. . Retrieved 2020/12/21.
• 2、 Mondal, Swapneswar,Dastidar, Parthasarathi. "Designing Metallogelators Derived from NSAID-based Zn(II) Coordination Complexes for Drug-Delivery Applications". . p. 3558 - 3567. Retrieved 2020/09/23.