1-Methoxymethanamine

Base Information

• Chemical Name: 1-Methoxymethanamine
• CAS No.: 57830-25-8
• Molecular Formula: C2H7NO
• Molecular Weight: 61.0837
• DSSTox Substance ID: DTXSID70590943
• Nikkaji Number: J1.148.855B
• Wikidata: Q82484561
• Mol file: 57830-25-8.mol

Synonyms:1-Methoxymethanamine;N-methoxy methylamine;57830-25-8;N-methoxy methyl-amine;DTXSID70590943;KZRAAPTWXAMZHQ-UHFFFAOYSA-N;AKOS006348074

Chemical Property of 1-Methoxymethanamine

Chemical Property:

• Melting Point: 142-144 °C
• Boiling Point: 57.6±23.0 °C(Predicted)
• PSA: 35.25000
• Density: 0.853±0.06 g/cm3(Predicted)
• LogP: 0.24930
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 61.052763847
• Heavy Atom Count: 4
• Complexity: 10

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COCN

Technology Process of 1-Methoxymethanamine

There total 1 articles about 1-Methoxymethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

→ methoxylmethyl amine (57830-25-8) + phenyl (3-methylisothiazol-5-yl)carbamate (70794-04-6)

Guidance literature:

Reference yield: 87.0%

methoxylmethyl amine (57830-25-8) + benzoic acid (3aS,4R,6R,6aR)-6-(2,6-dichloro-purin-9-yl)-2,2-dimethyl-tetrahydro-thieno[3,4-d][1,3]dioxol-4-ylmethyl ester (596103-10-5) → C22H24ClN5O5S

Guidance literature:

With triethylamine; In ethanol; at 20 ℃;

DOI:10.1016/j.bmcl.2008.01.070

Reference yield: 82.0%

N-benzyl-5-methyl-1H-imidazole-4-carboxylic acid + methoxylmethyl amine (57830-25-8) → N-methoxy-N-methyl-5-methyl-1-benzyl-1H-imidazole-4-carboxamide

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 16h;

Downstream raw materials:

N-methyl-N-methoxy-fluoroacetamide

N-chloroacetyl-2,6-dimethylanilinoacetic acid-N'-methyl-N'-methoxy amide

Refernces