Salvianolic acid A

Base Information

• Chemical Name: Salvianolic acid A
• CAS No.: 96574-01-5
• Molecular Formula: C26H22O10
• Molecular Weight: 494.45
• Hs Code.: 29189900
• UNII: 51622542XO
• ChEMBL ID: CHEMBL457077
• DSSTox Substance ID: DTXSID701316580
• Metabolomics Workbench ID: 70439
• Nikkaji Number: J470.628E
• Pharos Ligand ID: ZR34QG57BJZ7
• Wikidata: Q27108214
• Mol file: 96574-01-5.mol

Synonyms:(+)-salvianolic acid A;benzenepropanoic acid, alpha-(((2E)-3-(2-((1E)-2-(3,4-dihydroxyphenyl)ethenyl)-3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxy-, (alphaR)-;dan phenolic acid A;salvianolic acid A

Chemical Property of Salvianolic acid A

Chemical Property:

• Appearance/Colour: yellow solid
• Vapor Pressure: 2.04E-31mmHg at 25°C
• Melting Point: 164-167°C
• Refractive Index: 1.789
• Boiling Point: 858.7 °C at 760 mmHg
• PKA: 2.78±0.10(Predicted)
• Flash Point: 292.9 °C
• PSA: 184.98000
• Density: 1.58 g/cm³
• LogP: 3.34290
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: H2O: ≥19mg/mL
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 9
• Exact Mass: 494.12129689
• Heavy Atom Count: 36
• Complexity: 798

Purity/Quality:

99%, ^*data from raw suppliers

Salvianolic acid A ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C(C(=C(C=C2)O)O)C=CC3=CC(=C(C=C3)O)O)O)O
• Isomeric SMILES: C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C2=C(C(=C(C=C2)O)O)/C=C/C3=CC(=C(C=C3)O)O)O)O
• Recent ClinicalTrials: Efficacy and Safety of Salvianolic Acid on AIS
• Description: Salvianolic acid A is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties. It has been reported to reduce leukocyte-endothelial adherence, as well as inhibit inflammation and matrix metalloproteinases, suppress apoptosis, and reduce lipid peroxidation in damaged cardiac tissue.
• Uses: ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL.