(1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)-

Base Information

• Chemical Name: (1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)-
• CAS No.: 101018-79-5
• Molecular Formula: C₁₇H₁₉N₃OS
• Molecular Weight: 313.423
• Mol file: 101018-79-5.mol

Synonyms:(1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)-

Chemical Property of (1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)-

Chemical Property:

• Vapor Pressure: 4.34E-11mmHg at 25°C
• Boiling Point: 524.4°Cat760mmHg
• Flash Point: 270.9°C
• PSA: 66.37000
• Density: 1.36g/cm³
• LogP: 3.07200

Purity/Quality:

98%min ^*data from raw suppliers

(1)BENZOTHIOPYRANO(3,4-D)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)-

There total 2 articles about (1)BENZOTHIOPYRANO(3,4-d)IMIDAZOL-4(1H)-ONE, 1-METHYL-2-(1-PIPERIDINYL METHYL)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

piperidine (110-89-4) + 2-Chloromethyl-1-methyl-1H-thiochromeno[3,4-d]imidazol-4-one (101018-91-1) → 1-Methyl-2-piperidin-1-ylmethyl-1H-thiochromeno[3,4-d]imidazol-4-one (101018-79-5)

Guidance literature:

In benzene; for 8h; Heating;

DOI:10.1007/BF00766838

Reference yield:

3-amino-4-methylamino-thiochromen-2-one (66285-07-2) → 1-Methyl-2-piperidin-1-ylmethyl-1H-thiochromeno[3,4-d]imidazol-4-one (101018-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / 2 h / Heating

2: 81 percent / benzene / 8 h / Heating

In benzene;

DOI:10.1007/BF00766838

upstream raw materials:

piperidine

2-Chloromethyl-1-methyl-1H-thiochromeno[3,4-d]imidazol-4-one

3-amino-4-methylamino-thiochromen-2-one

Refernces