Technology Process of Ethyl 3-(chloromethyl)isonicotinate
There total 4 articles about Ethyl 3-(chloromethyl)isonicotinate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-chloro-succinimide; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane; acetic acid;
at 60 ℃;
Irradiation;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: selenium dioxide / diphenyl ether / 1.) 155 deg C, 0.5 h , 2.) 185 deg C, 0.5 h
2: 62 percent / hydrogen chloride (gas) / 4 h / Heating
3: N-chlorosuccinimide, azobisisobutyronitrile / acetic acid; CCl4 / 60 °C / Irradiation
With
hydrogenchloride; N-chloro-succinimide; selenium(IV) oxide; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane; diphenylether; acetic acid;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 62 percent / hydrogen chloride (gas) / 4 h / Heating
2: N-chlorosuccinimide, azobisisobutyronitrile / acetic acid; CCl4 / 60 °C / Irradiation
With
hydrogenchloride; N-chloro-succinimide; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane; acetic acid;
