(+/-)-2-(P-METHOXYPHENOXY)PROPIONIC ACID

Base Information

• Chemical Name: (+/-)-2-(P-METHOXYPHENOXY)PROPIONIC ACID
• CAS No.: 150436-68-3
• Molecular Formula: C₁₂H₁₄O₅
• Molecular Weight: 238.24
• Mol file: 150436-68-3.mol

Synonyms:Lactisole;Envision;Propanoic acid, 2-(4-methoxyphenoxy)-, sodium salt (9CI);

Chemical Property of (+/-)-2-(P-METHOXYPHENOXY)PROPIONIC ACID

Chemical Property:

• Appearance/Colour: White to pale cream crystalline solid
• PSA: 55.76000
• LogP: 1.54710
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Sodium2-(4-Methoxyphenoxy)propionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: Lactisole is an antagonist of sweet taste receptors, reducing both sweetness intensity and persistence. It blocks the activation of the sweet taste receptor T1R3 by natural and synthetic sweeteners and increases the inhibition of T1R2 by umami compounds. Lactisole can be used to explore the roles of these receptors in diverse pathways, including glucose-induced insulin secretion in pancreatic β-cells and the secretion of glucagon-like peptides by enteroendocrine L-cells.

Technology Process of (+/-)-2-(P-METHOXYPHENOXY)PROPIONIC ACID

There total 2 articles about (+/-)-2-(P-METHOXYPHENOXY)PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert.-butylhydroperoxide (75-91-2) + phthalic anhydride (85-44-9) → o-tert-butyldioxycarbonylbenzoic acid (15042-77-0)

Guidance literature:

With pyridine;

Reference yield:

→ o-tert-butyldioxycarbonylbenzoic acid (15042-77-0)

Guidance literature:

Phthaloylchlorid, t-Butylhydroperoxid;

DOI:10.1021/jo00818a044

upstream raw materials:

tert.-butylhydroperoxide

phthalic anhydride