potassium 4-dodecylbenzenesulphonate

Base Information

• Chemical Name: potassium 4-dodecylbenzenesulphonate
• CAS No.: 14564-74-0
• Molecular Formula: C18H30 O3 S . K
• Molecular Weight: 364.591
• Mol file: 14564-74-0.mol

Synonyms:Benzenesulfonicacid, 4-dodecyl-, potassium salt (9CI); Benzenesulfonic acid, p-dodecyl-,potassium salt (5CI)

Chemical Property of potassium 4-dodecylbenzenesulphonate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 65.58000
• Density: g/cm³
• LogP: 6.13490
• Storage Temp.: -20°C Freezer
• Solubility.: Methanol (Very Slightly, Heated), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

4-DodecylbenzenesulfonicAcidPotassiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Dodecylbenzenesulfonic Acid is developed as a small-molecule inhibitor targeting the pleckstrin homology domain of protein kinase B/AKT.

Technology Process of potassium 4-dodecylbenzenesulphonate

There total 1 articles about potassium 4-dodecylbenzenesulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-dodecylbenzene (123-01-3) → potassium 4-dodecylbenzenesulfonate (14564-74-0)

Guidance literature:

1-dodecylbenzene; With sulfuric acid; at 90 ℃; for 1h;

With potassium hydroxide; In water;

Reference yield: 97.0%

potassium 4-dodecylbenzenesulfonate (14564-74-0) → p-dodecylbenzenesulfonyl chloride (52499-14-6)

Guidance literature:

With trichlorophosphate; at 20 - 170 ℃;

Reference yield:

potassium 4-dodecylbenzenesulfonate (14564-74-0) → 4-dodecyl-N-(5-(5-(methylamino)pentyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide (1191951-93-5)

Guidance literature:

Multi-step reaction with 3 steps

1: trichlorophosphate / 20 - 170 °C

2: pyridine / 5 h / 20 °C

3: potassium carbonate / potassium iodide / water / 48 h / Heating; Reflux

With pyridine; potassium carbonate; trichlorophosphate; potassium iodide; In water;

upstream raw materials:

1-dodecylbenzene

Downstream raw materials:

p-dodecylbenzenesulfonyl chloride

ARC-183

4-dodecyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

4-dodecyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Refernces