Benzimidazo[1,2-c]quinazoline, 6-(phenylmethyl)-

Base Information

• Chemical Name: Benzimidazo[1,2-c]quinazoline, 6-(phenylmethyl)-
• CAS No.: 58980-15-7
• Molecular Formula: C21H15N3
• Molecular Weight: 309.37
• Mol file: 58980-15-7.mol

Synonyms:

Chemical Property of Benzimidazo[1,2-c]quinazoline, 6-(phenylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzimidazo[1,2-c]quinazoline, 6-(phenylmethyl)-

There total 7 articles about Benzimidazo[1,2-c]quinazoline, 6-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

3-benzyl-1,4,2-dioxazole-5-one (1401886-58-5) + 2-phenyl-1-p-toluenesulfonylbenzimidazole (15728-51-5) → 6-benzylbenzo[4,5]imidazo[1,2-c]quinazoline (58980-15-7)

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver bis(trifluoromethylsulfonyl)imide; In 1,2-dichloro-ethane; at 120 ℃; for 13h; Sealed tube;

DOI:10.1021/acs.joc.8b02396

Reference yield:

2-nitro-N-(2'-nitrophenyl)benzamide (54559-21-6) → 6-benzylbenzo[4,5]imidazo[1,2-c]quinazoline (58980-15-7)

Guidance literature:

Multi-step reaction with 2 steps

1: bei der Reduktion

2: phenylacetic acid ester

With phenylacetic acid ester;

Reference yield:

2-nitro-aniline (88-74-4) → 6-benzylbenzo[4,5]imidazo[1,2-c]quinazoline (58980-15-7)

Guidance literature:

Multi-step reaction with 3 steps

2: bei der Reduktion

3: phenylacetic acid ester

With phenylacetic acid ester;

upstream raw materials:

phenylacetic acid

2-(aminophenyl)benzimidazole

N-<2-aminobenzoil>-o-fenilendiamina

2-nitro-N-(2'-nitrophenyl)benzamide

Refernces