Chemical Property of Mycalolide-B
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Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.548
- Boiling Point:1042.294 °C at 760 mmHg
- Flash Point:584.158 °C
- PSA：260.75000
- Density:1.238 g/cm3
- LogP:7.39070
- Storage Temp.:-20°C
- Solubility.:Soluble in DMSO (up to 20 mg/ml)
- XLogP3:5
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:20
- Rotatable Bond Count:22
- Exact Mass:1026.50489690
- Heavy Atom Count:73
- Complexity:1810
- Purity/Quality:
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98% *data from raw suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1C(CC=CC2=NC(=CO2)C3=NC(=CO3)C4=NC(=CO4)C(C(C(=O)C=CCC(CC(=O)OC1CC(C(C)CCC(C(C)C(C(C)C=CN(C)C=O)OC(=O)C)OC(=O)C(COC)OC)OC)O)C)OC)OC
- Isomeric SMILES:C[C@@H]1[C@H](C/C=C\C2=NC(=CO2)C3=NC(=CO3)C4=NC(=CO4)[C@H]([C@H](C(=O)/C=C/C[C@@H](CC(=O)O[C@H]1C[C@@H]([C@@H](C)CC[C@H]([C@H](C)[C@@H]([C@H](C)/C=C/N(C)C=O)OC(=O)C)OC(=O)[C@@H](COC)OC)OC)O)C)OC)OC
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Description
Mycalolide B (122752-21-0) is a novel marine natural product which binds to actin in a 1:1 molar ratio (Kd=13-20 nM).1?It selectively and completely depolymerizes F-actin to G-actin?via?a novel mechanism different from that of the cytochalasin D.2?It is a novel and specific inhibitor of actomyosin ATPase.3
