Propanenitrile, 3-[(2-methylphenyl)thio]-

Base Information

• Chemical Name: Propanenitrile, 3-[(2-methylphenyl)thio]-
• CAS No.: 59309-64-7
• Molecular Formula: C10H11NS
• Molecular Weight: 177.27
• Mol file: 59309-64-7.mol

Synonyms:

Chemical Property of Propanenitrile, 3-[(2-methylphenyl)thio]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanenitrile, 3-[(2-methylphenyl)thio]-

There total 2 articles about Propanenitrile, 3-[(2-methylphenyl)thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acrylonitrile (107-13-1,25014-41-9) + 2-thiocresol (137-06-4) → 3-(o-tolylthio)propanenitrile (59309-64-7)

Guidance literature:

With β‐cyclodextrin; In water; acetone; at 20 ℃; for 0.166667h;

DOI:10.1039/b411736k

Reference yield:

→ 3-(o-tolylthio)propanenitrile (59309-64-7)

Guidance literature:

o-Thiokresol, Acrylonitril;

Reference yield:

3-(o-tolylthio)propanenitrile (59309-64-7) → 3-(toluene-2-sulfonyl)-propionic acid amide

Guidance literature:

Multi-step reaction with 2 steps

1: glacial acetic acid; aqueous H₂O₂ / anfangs unter Kuehlung, zuletzt bei 100grad

2: concentrated sulfuric acid / Eintragen des Reaktionsgemisches in Wasser von 0grad

With sulfuric acid; dihydrogen peroxide; acetic acid;

DOI:10.1021/ja01202a024

upstream raw materials:

acrylonitrile

2-thiocresol

Downstream raw materials:

3-(toluene-2-sulfonyl)-propionitrile

Refernces

• 1、 Kamal, Ahmed,Reddy, D. Rajasekhar,Rajendar. "A simple and green procedure for the conjugate addition of thiols to conjugated alkenes employing polyethylene glycol (PEG) as an efficient recyclable medium". . p. 7951 - 7953. Retrieved 2007/10/03.