[1,1'-Biphenyl]-2-carboxylicacid, 2'-nitro-

Base Information

• Chemical Name: [1,1'-Biphenyl]-2-carboxylicacid, 2'-nitro-
• CAS No.: 17294-89-2
• Molecular Formula: C13H9 N O4
• Molecular Weight: 243.219
• Mol file: 17294-89-2.mol

Synonyms:2-Biphenylcarboxylicacid, 2'-nitro- (6CI,7CI,8CI); 2-(2'-Nitrophenyl)benzoic acid;2-Nitro-2'-carboxybiphenyl; 2'-Nitro-1,1'-biphenyl-2-carboxylic acid;2'-Nitro-2-biphenylcarboxylic acid; NSC 263767

Chemical Property of [1,1'-Biphenyl]-2-carboxylicacid, 2'-nitro-

Chemical Property:

• Boiling Point: 405.3°Cat760mmHg
• Flash Point: 173.5°C
• Density: 1.358g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [1,1'-Biphenyl]-2-carboxylicacid, 2'-nitro-

There total 2 articles about [1,1'-Biphenyl]-2-carboxylicacid, 2'-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

2-Biphenylcarboxylic acid (947-84-2) → 2'-nitro-biphenyl-2-carboxylic acid (17294-89-2) + 4'-nitro-[1,1'-biphenyl]-2-carboxylic acid (18211-41-1)

Guidance literature:

With aminosulfonic acid; nitric acid; at 50 - 60 ℃; for 1h;

Reference yield:

6H-benzo[c]chromen-6-one (2005-10-9) → 2'-nitro-biphenyl-2-carboxylic acid (17294-89-2) + 4'-nitro-[1,1'-biphenyl]-2-carboxylic acid (18211-41-1)

Guidance literature:

With nitric acid; Multistep reaction; 70 deg C, 2 h;

DOI:10.1039/P19810000842

Reference yield:

2'-nitro-biphenyl-2-carboxylic acid (17294-89-2) → benzo[c]cinnoline-N-oxide (6141-98-6)

Guidance literature:

Multi-step reaction with 5 steps

1: SOCl₂

2: aqueous NH₃

3: aqueous KBrO

4: benzene

5: aq.-ethanolic KOH

With potassium hydroxide; ammonium hydroxide; thionyl chloride; potassium hypobromite; benzene;

upstream raw materials:

6H-benzo[c]chromen-6-one

2-Biphenylcarboxylic acid

Downstream raw materials:

6H-benzo[c]chromen-6-one

phenanthridin-6-ol

Bis-<2-(2-nitrophenyl)-benzoyl>-peroxid

6(5H)-phenanthridinone

Refernces

• 1、 Neustadt, Bernard R.,Smith, Elizabeth M.,Lindo, Neil,Nechuta, Terry,Bronnenkant, Alan,Wu, Arthur,Armstrong, Lydia,Kumar, Chandra. "Construction of a family of biphenyl combinatorial libraries: Structure- activity studies utilizing libraries of mixtures". . p. 2395 - 2398. Retrieved 1998.
• 2、 Gillis, Richard G.,Porter, Quentin N.. "The Fragment Ion C13H9O2 m/z 197 in the Mass Spectra of 2-(2'-R-phenyl)benzoic Acids". . p. 203 - 207. Retrieved 2007/10/02.