Benzeneacetaldehyde, 3-benzoyl-a-methyl-

Base Information

• Chemical Name: Benzeneacetaldehyde, 3-benzoyl-a-methyl-
• CAS No.: 60131-32-0
• Molecular Formula: C16H14O2
• Molecular Weight: 238.286
• Mol file: 60131-32-0.mol

Synonyms:

Chemical Property of Benzeneacetaldehyde, 3-benzoyl-a-methyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetaldehyde, 3-benzoyl-a-methyl-

There total 5 articles about Benzeneacetaldehyde, 3-benzoyl-a-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(3-(2-phenyl-1,3-dioxolan-2-yl)phenyl)propanal (74626-57-6) → R-2-(3-benzoylphenyl)-propionaldehyde (60131-32-0)

Guidance literature:

With iodine; acetone; for 1h; Inert atmosphere;

DOI:10.1021/ja910778p

Reference yield: 98.0%

2-(3-benzoylphenyl)propanal O-methyloxime → R-2-(3-benzoylphenyl)-propionaldehyde (60131-32-0)

Guidance literature:

With formaldehyd; Amberlyst 15; In water; acetone; at 80 ℃; for 2h;

DOI:10.1055/s-1993-25903

Reference yield:

2-(3-benzoylphenyl)-propanol → R-2-(3-benzoylphenyl)-propionaldehyde (60131-32-0)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 ℃;

DOI:10.1039/c005098a

upstream raw materials:

2-(3-(2-phenyl-1,3-dioxolan-2-yl)phenyl)propanal

Downstream raw materials:

(4R)-2-[1-(3-benzoylphenyl)-ethyl]-thiazolidine-4-carboxylic acid hydrochloride

(2S)-[3-(2-hydroxy-1-methyl-ethyl)-phenyl]-phenyl-methanone

Refernces

• 1、 Galletti, Paola,Emer, Enrico,Gucciardo, Gabriele,Quintavalla, Arianna,Pori, Matteo,Giacomini, Daria. "Chemoenzymatic synthesis of (2S)-2-arylpropanols through a dynamic kinetic resolution of 2-arylpropanals with alcohol dehydrogenases". supporting information; experimental part. p. 4117 - 4123. Retrieved 2010/10/03.
• 2、 -. "Method for producing (aryl substituted) carboxylic acid or its salt". . . Retrieved 2008/06/13.