Technology Process of 1,5,6-Heptanetriol, 3-(3-bromo-4-hydroxy-5-methylphenyl)-6-methyl-,
1-acetate, (3R)-
There total 10 articles about 1,5,6-Heptanetriol, 3-(3-bromo-4-hydroxy-5-methylphenyl)-6-methyl-,
1-acetate, (3R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1: PLE / dimethylsulfoxide
2: BOP; Et3N
3: LiBH4 / diethyl ether; ethanol
4: CSA / benzene
5: DIBAL-H / benzene
6: nBuLi / tetrahydrofuran
7: 92 percent / pyridine
8: 100 percent / AD-mix-α
9: H2 / Pd-C
10: C5H5NHBr3
With
pyridine; AD-mix-α; lithium borohydride; n-butyllithium; camphor-10-sulfonic acid; hydrogen; diisobutylaluminium hydride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; pyridinium hydrobromide perbromide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dimethyl sulfoxide; benzene;
6: Wittig reaction / 8: Sharpless asymmetric dihydroxylation;
DOI:10.1016/S0040-4039(03)01094-3
- Guidance literature:
-
Multi-step reaction with 5 steps
1: nBuLi / tetrahydrofuran
2: 92 percent / pyridine
3: 100 percent / AD-mix-α
4: H2 / Pd-C
5: C5H5NHBr3
With
pyridine; AD-mix-α; n-butyllithium; hydrogen; pyridinium hydrobromide perbromide;
palladium on activated charcoal;
In
tetrahydrofuran;
1: Wittig reaction / 3: Sharpless asymmetric dihydroxylation;
DOI:10.1016/S0040-4039(03)01094-3
- Guidance literature:
-
Multi-step reaction with 6 steps
1: DIBAL-H / benzene
2: nBuLi / tetrahydrofuran
3: 92 percent / pyridine
4: 100 percent / AD-mix-α
5: H2 / Pd-C
6: C5H5NHBr3
With
pyridine; AD-mix-α; n-butyllithium; hydrogen; diisobutylaluminium hydride; pyridinium hydrobromide perbromide;
palladium on activated charcoal;
In
tetrahydrofuran; benzene;
2: Wittig reaction / 4: Sharpless asymmetric dihydroxylation;
DOI:10.1016/S0040-4039(03)01094-3