CID 558009

Base Information

• Chemical Name: CID 558009
• CAS No.: 58546-55-7
• Molecular Formula: C₂₈H₃₄O₉
• Molecular Weight: 514.573
• Wikidata: Q104937565
• Mol file: 58546-55-7.mol

Synonyms:gomisin B;schisandrer B;schisantherin B

Chemical Property of CID 558009

Chemical Property:

• Vapor Pressure: 3.51E-17mmHg at 25°C
• Refractive Index: 1.588
• Boiling Point: 638.6 °C at 760 mmHg
• PKA: 13.54±0.60(Predicted)
• Flash Point: 206.4 °C
• PSA: 101.91000
• Density: 1.28 g/cm³
• LogP: 4.43340
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 514.22028266
• Heavy Atom Count: 37
• Complexity: 833

Purity/Quality:

98%,99%, ^*data from raw suppliers

Schizantherin B ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=C(C)C(=O)OC1C2=CC(=C(C(=C2C3=C(C4=C(C=C3CC(C1(C)O)C)OCO4)OC)OC)OC)OC
• Description: Schisantherin B (STB) is a lignan originally isolated from S. sphenanthera fruit. It inhibits formation of advanced glycation end products (AGEs) in vitro. STB (0.1 mg/kg) decreases escape latency in the Morris water maze and increases spontaneous alternation in the Y-maze in a mouse model of Alzheimer''s disease induced by amyloid-β (1-42) . It increases glial expression of glutamate transporter 1 (GLP-1) and decreases immobility time in the forced swim test (FST) in mice, indicating antidepressant-like activity. STB also increases spontaneous alternation in the Y-maze in a mouse model of stress-induced short-term learning impairment induced by the FST.
• Uses: Schisantherin B is a bioactive of lignans isolated from Schisandra chinesis which protect against cognitive deficits and neurodegeneration induced by Aβ1-42 in mice.