Disulfide,bis[(4-nitrophenyl)methyl]

Base Information

• Chemical Name: Disulfide,bis[(4-nitrophenyl)methyl]
• CAS No.: 39549-05-8
• Molecular Formula: C14H12 N2 O4 S2
• Molecular Weight: 336.392
• Mol file: 39549-05-8.mol

Synonyms:Disulfide,bis(p-nitrobenzyl) (6CI,7CI); Bis(4-nitrobenzyl) disulfide; NSC 338506

Chemical Property of Disulfide,bis[(4-nitrophenyl)methyl]

Chemical Property:

• Boiling Point: 534.4°Cat760mmHg
• Flash Point: 277°C
• Density: 1.434g/cm³

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Disulfide,bis[(4-nitrophenyl)methyl]

There total 19 articles about Disulfide,bis[(4-nitrophenyl)methyl] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C21H18N2O6S3 (95416-92-5) → bis(4-nitrobenzyl)disulfide (39549-05-8)

Guidance literature:

With cyclopenta-1,3-diene; triethylamine; In d⁽⁴⁾-methanol; benzene; for 24h; Ambient temperature;

DOI:10.1039/c39840001469

Reference yield: 96.0%

sodium 4-nitrobenzylsulfanesulfonate (94039-56-2) → bis(4-nitrobenzyl)disulfide (39549-05-8)

Guidance literature:

With 1H-imidazole; water; at 70 ℃; for 0.416667h; Green chemistry;

DOI:10.1080/10426507.2014.1003643

Reference yield: 84.0%

4-nitrobenzyl chloride (100-14-1) → bis(4-nitrobenzyl)disulfide (39549-05-8)

Guidance literature:

With N,N'-dibenzyl-N,N,N',N'-tetramethylethylenediammonium tetrahydroborate; sulfur; In methanol; at 20 ℃; for 0.0833333h;

DOI:10.1007/s00706-008-0950-0

upstream raw materials:

(p-nitrophenyl)methanethiol

benzyl-dithiocarbamic acid-(4-nitro-benzyl ester)

4-nitrobenzyl chloride

S-(4-Nitro-benzylmercapto)-thioglykolsaeure-methylester

Downstream raw materials:

tert-butyl 7β-<2-(2-tritylaminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido>-3-(4-nitrobenzylthio)-4-hydroxy-1-dethia-2-thiacepham-4-carboxylate

tert-butyl 7β-<2-(2-tritylaminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido>-3-(4-nitrobenzylthio)-1-dethia-2-thia-3-cephem-4-carboxylate

7β-<2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido>-3-(4-nitrobenzylthio)-1-dethia-2-thia-3-cephem-4-carboxylic acid

(2R,3S,4S,5R,6S)‐2‐(acetoxymethyl)‐6‐((4‐nitrobenzyl)thio)tetrahydro‐2H‐pyran‐3,4,5‐triyl triacetate

Refernces

• 1、 Abbasi, Mohammad,Mohammadizadeh, Mohammad Reza,Saeedi, Narges. "The synthesis of symmetrical disulfides by reacting organic halides with Na2S2O3·5H2O in DMSO". supporting information. p. 89 - 92. Retrieved 2016/01/12.
• 2、 Zhou, Yongsheng. "Deep eutectic mixture catalysed the synthesis of disulfides using Bunte salts as thiol surrogates". . p. 332 - 335. Retrieved 2015/08/18.