2,2-Bis(4-aminophenyl)hexafluoropropane

Base Information

• Chemical Name: 2,2-Bis(4-aminophenyl)hexafluoropropane
• CAS No.: 1095-78-9
• Molecular Formula: C15H12F6N2
• Molecular Weight: 334.264
• Hs Code.: 29215900
• Nikkaji Number: J2.207.822D
• Mol file: 1095-78-9.mol

Synonyms:Aniline,4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]di- (7CI);Aniline,4,4'-[trifluoro-1-(trifluoromethyl)ethylidene]di- (8CI);2,2-Bis(4-aminophenyl)hexafluoropropane;4,4'-(Hexafluoroisopropylidene)dianiline;BIS-A-AF;Hexafluoroisopropylidiene-4,4'-dianiline;

Chemical Property of 2,2-Bis(4-aminophenyl)hexafluoropropane

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 8.05E-08mmHg at 25°C
• Melting Point: 195-198 °C(lit.)
• Refractive Index: 1.587
• Boiling Point: 351.172 °C at 760 mmHg
• PKA: 3.98±0.25(Predicted)
• Flash Point: 159.438 °C
• PSA: 52.04000
• Density: 1.392 g/cm³
• LogP: 5.42410
• Water Solubility.: insoluble
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 2
• Exact Mass: 364.11226544
• Heavy Atom Count: 25
• Complexity: 424

Purity/Quality:

98% ^*data from raw suppliers

2,2-Bis(4-aminophenyl)hexafluoropropane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C(C2=CC(=C(C=C2)N)N)(C(F)(F)F)C(F)(F)F)N)N
• Uses: 2,2-Bis(4-aminophenyl)hexafluoropropane is used as a reactant in the crosslinking and stabilization of nanoparticle-filled polymethylpentyne nanocomposite membranes for gas separations.

Technology Process of 2,2-Bis(4-aminophenyl)hexafluoropropane

There total 9 articles about 2,2-Bis(4-aminophenyl)hexafluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.4%

4,4'-(hexafluoroisopropylidene)diphenol (1478-61-1) → 2,2-bis(4-aminophenyl)hexafluoropropane (1095-78-9)

Guidance literature:

With guanidine hydrochloride salt; nickel dichloride; In ethanol; at 85 ℃; under 1500.15 Torr; Solvent; Pressure; Temperature; Inert atmosphere; Autoclave;

Reference yield: 77.0%

C59H52F6N2 → 2,2-bis(4-aminophenyl)hexafluoropropane (1095-78-9)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 20 ℃; for 5h; Reflux;

Reference yield: 73.0%

C29H24F6N2 → 2,2-bis(4-aminophenyl)hexafluoropropane (1095-78-9)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; formic acid; at 20 - 30 ℃; for 20h; Reagent/catalyst; Solvent;

upstream raw materials:

2,2-bis(4-carboxyphenyl)hexafluoropropane

1,1,1,3,3,3-hexafluoro-2,2-di(p-tolyl)propane

4,4'-(hexafluoroisopropylidene)diphenol

2,2-bis(4-trifluoromethanesulfonyloxyphenyl)hexafluoropropane

Downstream raw materials:

N-{4-[1-(4-Acetylamino-phenyl)-2,2,2-trifluoro-1-trifluoromethyl-ethyl]-phenyl}-acetamide

4,4'-(perfluoropropane-2,2-diyl)bis(bromobenzene)

4,4'-(hexafluoroisopropylidene)bisphenyl isocyanate

Refernces

• 1、 -. "Preparation method of 2, 2-bis (4-aminophenyl) hexafluoropropane". . . Retrieved 2021/04/10.
• 2、 -. "Novel synthetic method for 2,2-bis(4-aminophenyl)hexafluoropropane". . . Retrieved 2018/09/08.