1-[2-Oxo-2-(2-pyridyl)ethyl]pyridinium Iodide

Base Information

• Chemical Name: 1-[2-Oxo-2-(2-pyridyl)ethyl]pyridinium Iodide
• CAS No.: 26482-00-8
• Molecular Formula: C12H11 N2 O . I
• Molecular Weight: 326.137
• European Community (EC) Number: 803-627-5
• DSSTox Substance ID: DTXSID10949350
• Mol file: 26482-00-8.mol

Synonyms:26482-00-8;1-[2-Oxo-2-(2-pyridyl)ethyl]pyridinium Iodide;Pan-W-15;Pyridinium,1-[2-oxo-2-(2-pyridinyl)ethyl]-, iodide (1:1);1-(2-Oxo-2-(pyridin-2-yl)ethyl)pyridin-1-ium iodide;1-((2-Pyridylcarbonyl)methyl)pyridinium iodide;2-pyridin-1-ium-1-yl-1-pyridin-2-ylethanone;iodide;1-2-(Pyridiloacetyl)-pyridinium iodide [Polish];Pyridinium, 1-((2-pyridylcarbonyl)methyl)-, iodide;1-2-(Pyridiloacetyl)-pyridinium iodide;1-[2-OXO-2-(PYRIDIN-2-YL)ETHYL]PYRIDIN-1-IUM IODIDE;SCHEMBL1930231;Pyridinium, 1-[2-oxo-2-(2-pyridinyl)ethyl]-, iodide;C12H11N2O.I;DTXSID10949350;C12-H11-N2-O.I;MFCD01690884;AKOS027250778;1-(2-PYRIDACYL)PYRIDINIUM IODIDE;AS-70138;LS-132898;1-(2-pyridylcarbonylmethyl)pyridinium iodide;CS-0450337;O0438;1-[2-oxo-2-(pyridyl)ethyl]pyridinium iodide;D91872;1-[2-(2-pyridyl)-2-oxoethyl]pyridinium iodide;1-(2-oxo-2-(pyridin-2-yl)ethyl)pyridinium iodide;1-(2-Oxo-2-(pyridin-2-yl)ethyl)pyridin-1-iumiodide;1-((PYRIDIN-2-YLCARBONYL)METHYL)PYRIDINIUM IODIDE;1-[2-Oxo-2-(2-pyridinyl)ethyl]pyridinium iodide, >=97.5% (HPLC)

Chemical Property of 1-[2-Oxo-2-(2-pyridyl)ethyl]pyridinium Iodide

Chemical Property:

• Melting Point: >300 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 33.84000
• Density: g/cm³
• LogP: -1.74400
• Solubility.: Methanol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 325.99161
• Heavy Atom Count: 16
• Complexity: 212

Purity/Quality:

98%,99%, ^*data from raw suppliers

PyridacylpyridiniumIodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 3577311
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=[N+](C=C1)CC(=O)C2=CC=CC=N2.[I-]
• Uses: Pyridacylpyridinium Iodide is an intermediate in the synthesis of genetic incorporation of a metal-ion chelating amino acids into proteins as a biophysical probe.

Technology Process of 1-[2-Oxo-2-(2-pyridyl)ethyl]pyridinium Iodide

There total 2 articles about 1-[2-Oxo-2-(2-pyridyl)ethyl]pyridinium Iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

pyridine (110-86-1) + 2-acetylpyridine (1122-62-9) → 1-(2-oxo-2-(2-pyridyl)ethyl)pyridinium iodide (26482-00-8)

Guidance literature:

With iodine;

DOI:10.1016/j.bmcl.2003.11.084

Reference yield: 72.0%

2-acetylpyridine (1122-62-9) → 1-(2-oxo-2-(2-pyridyl)ethyl)pyridinium iodide (26482-00-8)

Guidance literature:

With iodine; In pyridine;

Reference yield: 97.0%

1-(2-oxo-2-(2-pyridyl)ethyl)pyridinium iodide (26482-00-8) + (2E)-3-(4-nitrophenyl)-1-(pyridin-2-yl)prop-2-en-1-one (18451-69-9) → 4’-(4-nitrophenyl)-2,2’,6’,2’’-terpyridine (129077-51-6)

Guidance literature:

With ammonium acetate; In methanol; for 24h; Heating;

DOI:10.1002/hlca.19930760323

upstream raw materials:

pyridine

2-acetylpyridine

Downstream raw materials:

4-(4-methoxy-phenyl)-[2,2']bipyridinyl

4′-(3,4-dimethoxyphenyl)-2,2′:6′,2″-terpyridine

4′-(3-nitrophenyl)-2,2′:6′,2″-terpyridine

4',4''-diphenyl-2,2':6',2'':6'',2'''-quaterpyridine

Refernces

• 1、 Belhadj, Esmah,El-Ghayoury, Abdelkrim,Mazari, Miloud,Sallé, Marc. "The parent tetrathiafulvalene-terpyridine dyad: Synthesis and metal binding properties". . p. 3051 - 3054. Retrieved 2013.
• 2、 H?rner, Gerald,Klein, Axel,Sandleben, Aaron,Sivchik, Vasily,Vogt, Nicolas. "Direct base-assisted C-H cyclonickelation of 6-phenyl-2,20-bipyridine". . . Retrieved 2020.
• 3、 Labra-Vázquez, Pablo,Palma-Contreras, Miguel,Santillan, Rosa,Farfán, Norberto. "Vibrational, structural and electronic study of a pyridinium salt assisted by SXRD studies and DFT calculations". . p. 156 - 162. Retrieved 2017.
• 4、 Huang, Yangwei,Lin, Qian,Wu, Jiaming,Fu, Nanyan. "Design and synthesis of a squaraine based near-infrared fluorescent probe for the ratiometric detection of Zn2+ ions". . p. 699 - 704. Retrieved 2013.
• 5、 Delente, Jason M.,Gunnlaugsson, Thorfinnur,Kotova, Oxana,Shanmugaraju, Sankarasekaran,Umadevi, Deivasigamani,Watson, Graeme W.. "Aggregation induced emission (AIE) active 4-amino-1,8-naphthalimide-Tr?ger's base for the selective sensing of chemical explosives in competitive aqueous media". supporting information. p. 2562 - 2565. Retrieved 2020/03/10.