2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE

Base Information

• Chemical Name: 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE
• CAS No.: 4107-01-1
• Molecular Formula: C21H19NO
• Molecular Weight: 301.388
• Hs Code.: 2924299090
• Mol file: 4107-01-1.mol

Synonyms:diphenyl-acetic acid p-toluidide;N-p-tolyl-diacetamide;N,N-Diacetyl-toluidin;N,N-Diacetyl-4-methylanilin;Diphenylacet-<4-methyl-anilid>;N,N-diacetyl-p-toluidine;4-tolyldiphenylacetamide;Diphenyl-essigsaeure-p-toluidid;2,2-diphenyl-N-p-tolyl-acetamide;Diacetyl-p-toluidin;4-methyl-diacetanilide;N-p-tolyldiphenylacetamide;p-Diacetotoluidide;N-Acetyl-N-p-tolyl-acetamide;N-p-Tolyl-diacetamid;

Chemical Property of 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE

Chemical Property:

• Vapor Pressure: 1.71E-10mmHg at 25°C
• Boiling Point: 509.3°C at 760 mmHg
• Flash Point: 309.7°C
• PSA: 29.10000
• Density: 1.144g/cm³
• LogP: 4.83860

Purity/Quality:

99% ^*data from raw suppliers

2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE

There total 28 articles about 2,2-DIPHENYL-N-P-TOLYL-ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-(2,2-diphenyl-1-chlorovinyl)-N-(dimethylaminodichloromethyl)-p-toluidine (91374-51-5) → N-(p-tolyl)diphenylacetamide (4107-01-1) + 1-(2,2-diphenyl-1-chlorovinyl)-1-p-tolyl-2,2-dimethylurea (91374-52-6)

Guidance literature:

With water; In tetrahydrofuran; overnight;

Reference yield: 82.0%

diphenylketene-N-p-tolylimine (5110-45-2,73940-93-9) + dichloromethylenedimethyliminium chloride (33842-02-3,529510-96-1) → N-(p-tolyl)diphenylacetamide (4107-01-1) + N-(2,2-diphenyl-1-chlorovinyl)-N-(dimethylaminodichloromethyl)-p-toluidine (91374-51-5)

Guidance literature:

In chloroform; for 48h; Ambient temperature;

Reference yield: 72.0%

p-toluidine (106-49-0,12221-03-3) + acetic acid (64-19-7,77671-22-8) → N-(p-tolyl)diphenylacetamide (4107-01-1) + 4-Methylacetanilide (103-89-9)

Guidance literature:

With Diphenylketene p-tolylimine; In acetonitrile; for 20h; Rate constant; Product distribution;

upstream raw materials:

diphenylketene-N-p-tolylimine

diphenylacetic acid chloride

p-toluidine

diethyl ether

Downstream raw materials:

N-(2,2-diphenyl-1-chlorovinyl)-N-(dimethylaminodichloromethyl)-p-toluidine

diphenylketene-N-p-tolylimine

di-tert-butyl-methylphosphine oxide

C₉H₂₁Cl₂P

Refernces

• 1、 Nunes, Jose,Kascheres, Albert. "Site Selectivity in the Reaction of Formyl-2H-azirine-N-arylimines with Diphenylketene". . p. 341 - 344. Retrieved 2007/10/03.
• 2、 Mironova, D. F.,Vykhrestyuk, N. I.,Kukhar', V. P.. "ADDITION AT THE C=N BOND IN KETENE IMINES. REACTION OF DIPHENYLKETENE N-(p-TOLYL)IMINE WITH N,N-DIMETHYLDICHLOROMETHYLENEAMMONIUM CHLORIDE". . p. 242 - 245. Retrieved 2007/10/02.