1,8-Dichloroanthraquinone

Base Information

• Chemical Name: 1,8-Dichloroanthraquinone
• CAS No.: 82-43-9
• Molecular Formula: C14H6Cl2O2
• Molecular Weight: 277.106
• Hs Code.: 2914700090
• European Community (EC) Number: 201-420-9
• NSC Number: 7209
• UNII: HNW5L47GP6
• DSSTox Substance ID: DTXSID8058873
• Nikkaji Number: J53.414E
• Wikidata: Q81988566
• Mol file: 82-43-9.mol

Synonyms:1,8-Dichloroanthraquinone;82-43-9;1,8-dichloroanthracene-9,10-dione;9,10-Anthracenedione, 1,8-dichloro-;1,8-Dichloranthrachinon;1,8-Dichloro-9,10-anthraquinone;ANTHRAQUINONE, 1,8-DICHLORO-;C14H6Cl2O2;AI3-38302;1,8-Dichloranthrachinon [Czech];NSC 7209;EINECS 201-420-9;MFCD00001191;BRN 1979205;NSC-7209;4-07-00-02560 (Beilstein Handbook Reference);NSC7209;1,8-dichloranthraquinon;9, 1,8-dichloro-;Anthraquinone,8-dichloro-;HNW5L47GP6;Anthraquinone, 1,8-dichloro;SCHEMBL122441;DTXSID8058873;1,8-Dichloroanthraquinone, 97%;WLN: L C666 BV IVJ DG NG;1,8-Dichloroanthra-9,10-quinone #;AKOS001028817;AC-11725;AS-14373;LS-20662;SY018902;CS-0155812;D0329;FT-0607043;H11759;A840333;W-104177;Z56779220

Chemical Property of 1,8-Dichloroanthraquinone

Chemical Property:

• Appearance/Colour: yellow powder
• Vapor Pressure: 1.79E-08mmHg at 25°C
• Melting Point: 201.5-203 °C(lit.)
• Refractive Index: 1.671
• Boiling Point: 455.2 °C at 760 mmHg
• Flash Point: 191.7 °C
• PSA: 34.14000
• Density: 1.514 g/cm³
• LogP: 3.76880
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: Slightly soluble in water.
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 275.9744848
• Heavy Atom Count: 18
• Complexity: 350

Purity/Quality:

99% ^*data from raw suppliers

1,8-Dichloroanthraquinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Dyes -> Anthraquinone Dyes
• Canonical SMILES: C1=CC2=C(C(=C1)Cl)C(=O)C3=C(C2=O)C=CC=C3Cl
• Uses: 1,8-Dichloroanthraquinone is a reagent in the preparation of anthraquinones, which has antitumor activities. It is used as primary and secondary intermediate.

Technology Process of 1,8-Dichloroanthraquinone

There total 15 articles about 1,8-Dichloroanthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloroanthracene-9,10-dione (82-44-0) + 2-chloroanthracene-9,10-dione (131-09-9) → 1,8-dichloroanthraquinone (82-43-9) + 1,4,8-Trichloroanthraquinone (1594-64-5)

Guidance literature:

In aqueous sodium chlorate;

Reference yield:

1,8-anthraquinonedisulphonic acid (82-48-4) → 1,8-dichloroanthraquinone (82-43-9)

Guidance literature:

With hydrogenchloride; Irradiation;

Reference yield:

→ 1,8-dichloroanthraquinone (82-43-9)

Guidance literature:

With tetrachloromethane; thionyl chloride; at 170 ℃;

upstream raw materials:

1,8-anthraquinonedisulphonic acid

1,8-diamino-anthraquinone

anthracene-1,8-disulphonic acid

hydrogenchloride

Downstream raw materials:

1,8-bis(p-tolylamino)anthraquinone

1,8-bis-(2-hydroxy-ethylamino)-anthraquinone

1,8-Dichloro-10-(diphenyl-phosphinoylmethyl)-10-hydroxy-10H-anthracen-9-one

1,8-dichloroanthracene

Refernces

• 1、 -. "Process for concentrating halogenoanthraquinones". . . Retrieved 2008/06/13.