Codeine methylbromide

Base Information

• Chemical Name: Codeine methylbromide
• CAS No.: 125-27-9
• Molecular Formula: Br*C₁₉H₂₄NO₃
• Molecular Weight: 394.308
• UNII: 25007U9T7H
• DSSTox Substance ID: DTXSID10924985
• Wikipedia: Codeine_methylbromide
• Wikidata: Q5140136
• Metabolomics Workbench ID: 146132
• Mol file: 125-27-9.mol

Synonyms:Codeine methylbromide;Eucodin;CODEINE METHYL BROMIDE;Codeine bromomethylate;125-27-9;UNII-25007U9T7H;25007U9T7H;C19H24NO3.Br;DEA No. 9070;SCHEMBL907309;DTXSID10924985;CODEINE METHYL BROMIDE [MI];Morphinanium, 7,8-didehydro-17,17-dimethyl-4,5-alpha-epoxy-6-alpha-hydroxy-3-methoxy-, bromide;CODEINE METHYLBROMIDE, (-)-;DB01477;Q5140136;MORPHINANIUM, 7,8-DIDEHYDRO-4,5-EPOXY-6-HYDROXY-3-METHOXY-17,17-DIMETHYL-, BROMIDE (1:1), (5.ALPHA.,6.ALPHA.)-

Chemical Property of Codeine methylbromide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 393.09396
• Heavy Atom Count: 24
• Complexity: 547

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1(CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O)C.[Br-]
• Isomeric SMILES: C[N+]1(CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O)C.[Br-]

Technology Process of Codeine methylbromide

There total 1 articles about Codeine methylbromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl bromide (74-83-9) + codeine (76-57-3) → 4,5α-epoxy-6α-hydroxy-3-methoxy-17,17-dimethyl-morphin-7-enium; bromide (125-27-9)

Guidance literature:

With chloroform;

upstream raw materials:

methyl bromide

codeine