2-Propyloxybenzaldehyde

Base Information

• Chemical Name: 2-Propyloxybenzaldehyde
• CAS No.: 7091-12-5
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Hs Code.: 2912499000
• Mol file: 7091-12-5.mol

Synonyms:Benzaldehyde,o-propoxy- (6CI,7CI,8CI);2-Propoxybenzaldehyde;NSC 68512;o-Propoxybenzaldehyde;

Chemical Property of 2-Propyloxybenzaldehyde

Chemical Property:

• Vapor Pressure: 0.00963mmHg at 25°C
• Melting Point: 173-174 °C
• Refractive Index: 1.531
• Boiling Point: 264.6°Cat760mmHg
• Flash Point: 113.2°C
• PSA: 26.30000
• Density: 1.038g/cm³
• LogP: 2.28790
• Sensitive.: Air Sensitive

Purity/Quality:

99% ^*data from raw suppliers

2-Propoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propyloxybenzaldehyde

There total 9 articles about 2-Propyloxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(allyloxy)benzaldehyde (28752-82-1) → 2-n-propoxybenzaldehyde (7091-12-5)

Guidance literature:

With hydrogen; palladium; In ethyl acetate; for 27h;

DOI:10.1016/S0040-4039(02)02472-3

Reference yield: 89.0%

salicylaldehyde (90-02-8) + 1-iodo-propane (107-08-4) → 2-n-propoxybenzaldehyde (7091-12-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 18h;

DOI:10.1016/j.ejmech.2014.11.017

Reference yield: 88.0%

C10H12N2O + 2-phenyl-1,3,2-benzodioxaborole (5747-23-9) → 2-n-propoxybenzaldehyde (7091-12-5) + phenol (108-95-2,27073-41-2)

Guidance literature:

With oxygen; In acetonitrile; at 32 ℃; for 4h; under 760.051 Torr; Schlenk technique;

DOI:10.1002/ejoc.201501222

upstream raw materials:

salicylaldehyde

1-iodo-propane

2-(3-bromopropyloxy)benzaldehyde

2-(allyloxy)benzaldehyde

Downstream raw materials:

(2-propoxy-phenyl)-acetone

1-(1-benzylpiperidin-4-yl)-2-(2-n-propoxyphenyl)ethanone

2-Propoxy-benzylbromid

2H-benzo[e][1,4]dioxepin-5(3H)-one

Refernces

• 1、 Ohashi, Masao,Gamo, Kanae,Tanaka, Yuta,Waki, Minoru,Beniyama, Yoko,Matsuno, Kenji,Wada, Jun,Tenta, Masafumi,Eguchi, Jun,Makishima, Makoto,Matsuura, Nobuyasu,Oyama, Takuji,Miyachi, Hiroyuki. "Structural design and synthesis of arylalkynyl amide-type peroxisome proliferator-activated receptor γ3 (PPAR γ3)-selective antagonists based on the helix12-folding inhibition hypothesis". . p. 53 - 67. Retrieved 2015/01/08.
• 2、 Mori, Akinori,Miyakawa, Yumi,Ohashi, Eri,Haga, Tomoko,Maegawa, Tomohiro,Sajiki, Hironao. "Pd/C-catalyzed chemoselective hydrogenation in the presence of diphenylsulfide". . p. 3279 - 3281. Retrieved 2007/10/03.