Gaboxadol hydrochloride

Base Information Edit

Chemical Name:Gaboxadol hydrochloride
CAS No.:64603-91-4
Molecular Formula:C6H8 N2 O2
Molecular Weight:140.142
Hs Code.:
European Community (EC) Number:285-687-7
NSC Number:759585
UNII:478RVH3TVD
DSSTox Substance ID:DTXSID90234251
Wikidata:Q27259031
ChEMBL ID:CHEMBL1255746
Mol file:64603-91-4.mol

Synonyms:GABOXADOL HYDROCHLORIDE;THIP hydrochloride;85118-33-8;Gaboxadol (hydrochloride);Gaboxadol HCl;UNII-478RVH3TVD;478RVH3TVD;85118-33-8 (HCl);4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride;4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3(2H)-one monohydrochloride;EINECS 285-687-7;4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one hydrochloride;4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HCL, GABOXADOL-HCL;Lu 02-030 (hydrochloride);THIP (hydrochloride);4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one monohydrochloride;SR-01000075651;4,5,6,7-Tetrahydro-isoxazolo[5,4-c]pyridin-3(2H)-one;4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3(2H)-one hydrate;THIP HCl;(THIP);D00XNY;MLS002154080;SPECTRUM1503648;CHEMBL1255746;DTXSID90234251;HMS1571C05;Pharmakon1600-01503648;BCP16610;GABOXADOL HYDROCHLORIDE [MI];Tox21_501233;CCG-39368;MFCD00055180;NSC759585;AKOS024015212;LP01233;NCGC00094475-01;NCGC00094475-02;NCGC00094475-03;NCGC00094475-04;NCGC00261918-01;AS-53745;BP-12453;HY-10233;SMR000875361;J Med Chem 26: 895 (1983);CS-0002508;EU-0101233;G0405;T-101;EN300-152453;P17040;Gaboxadol hydrochloride, solid, >=98% (HPLC);SR-01000075651-1;SR-01000075651-3;SR-01000075651-6;SR-01000075651-7;4,5,6,7-tetrahydroisoxazolo-[5,4-c]-pyridin-3-ol;Q27259031;9-Oxa-3,8-Diazabicyclo[4.3.0]Non-10-En-7-one HCl;Z2688689710;4H,5H,6H,7H-[1,2]oxazolo[5,4-c]pyridin-3-ol hydrochloride;4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-onehydrochloride;4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one;hydrochloride;ISOXAZOLO(5,4-C)PYRIDIN-3(2H)-ONE, 4,5,6,7-TETRAHYDRO-, HYDROCHLORIDE (1:1);ISOXAZOLO(5,4-C)PYRIDIN-3(2H)-ONE, 4,5,6,7-TETRAHYDRO-, MONOHYDROCHLORIDE

Suppliers and Price of Gaboxadol hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
THIP hydrochloride
50mg
$ 403.00

Tocris
THIPhydrochloride ≥98%(HPLC)
50
$ 162.00

ChemScene
THIP 99.36%
25mg
$ 90.00

Biorbyt Ltd
THPO
10 μg
$ 290.70

American Custom Chemicals Corporation
GABOXADOL 95.00%
50MG
$ 685.21

Total 79 raw suppliers

Chemical Property of Gaboxadol hydrochloride Edit

Chemical Property:

Appearance/Colour:white solid
Vapor Pressure:0.00113mmHg at 25°C
Melting Point:242-244° (dec)
Boiling Point:340.5 °C at 760 mmHg
PKA:pKa (water, 25°): 4.44 ±0.03; 8.48 ±0.04
Flash Point:159.7 °C
PSA：58.29000
Density:1.36 g/cm³
LogP:1.15670
Storage Temp.:Store at RT
Solubility.:ethanol: 0.91 mg/mL
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:176.0352552
Heavy Atom Count:11
Complexity:210

Purity/Quality:

98%,99%, ^*data from raw suppliers

THIP hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): A poison.
Hazard Codes:A poison.
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC2=C1C(=O)NO2.Cl
Description Gaboxadol HCl (64603-91-4) is a GABA-A receptor agonist. Hypnotic agent.
Uses GABAa agonist, GABAc antagonist

Technology Process of Gaboxadol hydrochloride

There total 4 articles about Gaboxadol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: