Bromodichloromethane

Base Information

• Chemical Name: Bromodichloromethane
• CAS No.: 75-27-4
• Molecular Formula: CH Br Cl2
• Molecular Weight: 163.829
• European Community (EC) Number: 200-856-7
• ICSC Number: 0393
• NSC Number: 8018
• UN Number: 2810,3082
• UNII: 7LN464CH2O
• DSSTox Substance ID: DTXSID1020198
• Nikkaji Number: J1.448F
• Wikipedia: Bromodichloromethane
• Wikidata: Q417426
• NCI Thesaurus Code: C44345
• Metabolomics Workbench ID: 54994
• ChEMBL ID: CHEMBL346231
• Mol file: 75-27-4.mol

Synonyms:bromodichloromethane;bromodichloromethane, 14C-labeled;bromodichloromethane, ion(1-);dichlorobromomethane

Chemical Property of Bromodichloromethane

Chemical Property:

• Appearance/Colour: 2810
• Vapor Pressure: 65.3mmHg at 25°C
• Melting Point: ?55 °C(lit.)
• Boiling Point: 87 °C(lit.)
• Flash Point: 1.3 °C
• PSA: 0.00000
• Density: 1.98 g/mL at 25 °C(lit.)
• LogP: 2.14250
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 161.86387
• Heavy Atom Count: 4
• Complexity: 13.5
• Transport DOT Label: Poison

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn:Harmful
• Statements: R22:Harmful if swallowed.; R40:Possible risks of irreversible effects.
• Safety Statements: S36/37:Wear suitable protective clothing and gloves.; S45:In case of accident of if you feel unwell, seek medical advice

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Brominated Solvents
• Canonical SMILES: C(Cl)(Cl)Br
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Long Term Exposure: Ingestion may cause effects on the kidneys and liver. This may result in impaired functions. This substance is possibly carcinogenic to humans.

Technology Process of Bromodichloromethane

There total 64 articles about Bromodichloromethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ bromodichloromethane (75-27-4) + chloroform (67-66-3,8013-54-5) + chlorodibromomethane (124-48-1) + Bromoform (75-25-2)

Guidance literature:

With bromine; chlorine; In phosphate buffer; at 25 ℃; for 24h; pH=7.0; Further byproducts given; Formation of xenobiotics;

DOI:10.1016/S0045-6535(00)00210-1

Reference yield:

dichloromethane (75-09-2) → bromodichloromethane (75-27-4) + chloroform (67-66-3,8013-54-5)

Guidance literature:

With bromine; chlorine; In trichlorofluoromethane; at 10 ℃; for 0.0166667h; Yield given; Irradiation;

DOI:10.1016/S0040-4039(00)85163-1

Reference yield:

chloride (16887-00-6) + chloroperoxidase → bromodichloromethane (75-27-4) + chloroform (67-66-3,8013-54-5) + chlorodibromomethane (124-48-1) + 1,1-Dichloroacetone (513-88-2)

Guidance literature:

With dihydrogen peroxide; potassium carbonate; In phosphate buffer; Further byproducts given; Enzymatic reaction;

DOI:10.1016/S0045-6535(98)00100-3

upstream raw materials:

ethyl bromide

chloroform

methane

dichloromethane

Downstream raw materials:

1-bromo-1,2-dichloro-ethane

2-bromo-1,3-dichloropropane

1-bromo-3-chloro-2-chloromethyl-propane

9,9-dichlorobicyclo[6.1.0]nonane

Refernces

• 1、 Walling, Cheves,El-Taliawi, Gamil,Sopchik, Alan. "Some Observations on N-Chlorosuccinimide Halogenations. A New Bromination Technique". . p. 736 - 738. Retrieved 1986.
• 2、 Chang,Lin,Chiang. "Effects of bromide on the formation of THMs and HAAs". . p. 1029 - 1034. Retrieved 2007/10/03.
• 3、 Ichihashi, Keiko,Teranishi, Kiyoshi,Ichimura, Akio. "Brominated-trihalomethane formation from phenolic derivatives as a model of humic materials by the reaction with hypochlorite and hypobromite ions". . p. 957 - 958. Retrieved 2007/10/03.