5-Decyn-1-ol

Base Information

• Chemical Name: 5-Decyn-1-ol
• CAS No.: 68274-97-5
• Molecular Formula: C10H18O
• Molecular Weight: 154.252
• European Community (EC) Number: 269-529-4
• UNII: LDL5G6522J
• DSSTox Substance ID: DTXSID7071365
• Nikkaji Number: J289.123I
• Wikidata: Q81998978
• Mol file: 68274-97-5.mol

Synonyms:5-Decyn-1-ol;68274-97-5;dec-5-yn-1-ol;LDL5G6522J;EINECS 269-529-4;UNII-LDL5G6522J;5-Decyn-1-ol, 97%;DTXSID7071365;SCHEMBL12680241;MFCD00464353;5-DECYN-1-OL, 96%,;AKOS006338468;AS-81479;CS-0360772

Chemical Property of 5-Decyn-1-ol

Chemical Property:

• Vapor Pressure: 0.01mmHg at 25°C
• Melting Point: 1.9°C (estimate)
• Refractive Index: n20/D 1.4610(lit.)
• Boiling Point: 233.9 °C at 760 mmHg
• Flash Point: 98.9 °C
• PSA: 20.23000
• Density: 0.884 g/cm³
• LogP: 2.34260
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 154.135765193
• Heavy Atom Count: 11
• Complexity: 126

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Decyn-1-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCC#CCCCCO
• Uses: 5-Decyn-1-ol is used in the synthesis of multi-substituted cyclopropanes. It involved in manufacture of fine chemicals, having applications in electroplating and perfumery industry.

Technology Process of 5-Decyn-1-ol

There total 25 articles about 5-Decyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(1-butoxyethoxy)dec-5-yne (117968-00-0) → dec-5-yn-1-ol (68274-97-5)

Guidance literature:

With cation-exchange resin KU-2-8 H⁽¹⁺⁾ form; In methanol; for 5h; Ambient temperature;

DOI:10.1007/BF00597601

Reference yield: 76.0%

n-butyllithium (109-72-8,29786-93-4) + C7H10Cl2O (1352757-62-0) → dec-5-yn-1-ol (68274-97-5)

Guidance literature:

In diethyl ether; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/chem.201404873

Reference yield: 62.0%

dec-1-en-5-yne (82511-32-8) → dec-5-yn-1-ol (68274-97-5)

Guidance literature:

dec-1-en-5-yne; With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; water; at 0 - 70 ℃;

upstream raw materials:

1-bromo-butane

5-hexyl-1-ol

oxirane

1-bromo-oct-3-yne

Downstream raw materials:

deca-1,5-diyne

1-Decanol

dec-5-yn-1-yl benzoate

2-pentyl-1-phenylpiperidine-2-carbonitrile

Refernces

• 1、 Shimkin, Kirk W.,Montgomery, John. "Synthesis of Tetrasubstituted Alkenes by Tandem Metallacycle Formation/Cross-Electrophile Coupling". supporting information. p. 7074 - 7078. Retrieved 2018/06/04.
• 2、 Jindal, Rani,Devi, Aarti,Kad, Goverdhan L.,Singh, Jasvinder. "Synthesis of heneicos-6(Z)-en-11-one, dec-5(Z)-en-l-yl acetate, dec-5(Z)-En-1-y1-3-methylbutanoate (insect sex pheromones)". experimental part. p. 495 - 499. Retrieved 2010/10/20.