ETHYL M-ETHOXYBENZOATE

Base Information

• Chemical Name: ETHYL M-ETHOXYBENZOATE
• CAS No.: 5432-17-7
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Hs Code.: 2918990090
• Mol file: 5432-17-7.mol

Synonyms:Ethyl 3-ethoxybenzoate;NSC 7016;Ethyl m-ethoxybenzoate;

Chemical Property of ETHYL M-ETHOXYBENZOATE

Chemical Property:

• Vapor Pressure: 0.00996mmHg at 25°C
• Refractive Index: n20/D 1.508(lit.)
• Boiling Point: 264 °C at 760 mmHg
• Flash Point: 110.3 °C
• PSA: 35.53000
• Density: 1.053 g/cm³
• LogP: 2.26200

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 3-ethoxybenzoate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 23-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of ETHYL M-ETHOXYBENZOATE

There total 6 articles about ETHYL M-ETHOXYBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethyl bromide (74-96-4) + ethyl-3-hydroxybenzoate (7781-98-8) → 3-ethoxybenzoic acid ethyl ester (5432-17-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.3390/md12041839

Reference yield: 93.0%

ethyl iodide (75-03-6) + 3-Carboxyphenol (99-06-9) → 3-ethoxybenzoic acid ethyl ester (5432-17-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 3h;

DOI:10.1021/jm00019a014

Reference yield: 74.0%

ethanol (64-17-5) + ethyl 3-bromobenzoate (24398-88-7) → 3-ethoxybenzoic acid ethyl ester (5432-17-7)

Guidance literature:

With copper(l) iodide; N¹, N²-diphenethyloxalamide; sodium t-butanolate; In 1,4-dioxane; for 24h; Schlenk technique; Inert atmosphere; Molecular sieve; Heating;

DOI:10.1021/jacs.8b12142

upstream raw materials:

ethyl bromide

ethyl-3-hydroxybenzoate

ethyl iodide

3-Carboxyphenol

Downstream raw materials:

3-(3-ethoxyphenyl)-3-oxopropanenitrile

3-ethoxybenzoylhydrazide

N-[(2R,3R,3aS,9aR)-2-(6-Amino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl]-3-ethoxy-benzamide

ethyl 3-(benzoyloxy)benzoate

Refernces

• 1、 Hashimoto, Toru,Shiota, Keisuke,Funatsu, Kei,Yamaguchi, Yoshitaka. "Cross-Coupling Reactions of Aryl Halides with Primary and Secondary Aliphatic Alcohols Catalyzed by an O,N,N-Coordinated Nickel Complex". supporting information. p. 1625 - 1630. Retrieved 2021/01/26.
• 2、 Jumbam, Ndze D.,Maganga, Yamkela,Masamba, Wayiza,Mbunye, Nomthandazo I.,Mgoqi, Esethu,Mtwa, Sphumusa. "Unprecedented alkylation of carboxylic acids by boron trifluoride etherate". . p. 387 - 392. Retrieved 2018/09/06.