Oxazolidine

Base Information

• Chemical Name: Oxazolidine
• CAS No.: 504-76-7
• Molecular Formula: C3H7 N O
• Molecular Weight: 73.0947
• Hs Code.: 2934999090
• European Community (EC) Number: 610-533-6
• UNII: 13F52UF6MR
• DSSTox Substance ID: DTXSID50198446
• Nikkaji Number: J327.243E
• Wikipedia: Oxazolidine
• Wikidata: Q417695
• Metabolomics Workbench ID: 57404
• ChEMBL ID: CHEMBL4297314
• Mol file: 504-76-7.mol

Synonyms:1,3-oxazolidine;oxazolidine

Chemical Property of Oxazolidine

Chemical Property:

• Vapor Pressure: 38.7mmHg at 25°C
• Melting Point: 90 °C(Solv: benzene (71-43-2))
• Boiling Point: 99.2°Cat760mmHg
• PKA: 8.28±0.20(Predicted)
• Flash Point: 18.8°C
• PSA: 21.26000
• Density: 0.964g/cm³
• LogP: -0.10750
• Storage Temp.: -86?C Freezer
• Solubility.: Acetone
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 73.052763847
• Heavy Atom Count: 5
• Complexity: 30.1

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Uses -> Biocides/Disinfectants
• Canonical SMILES: C1COCN1
• Recent ClinicalTrials: Efficacy and Safety of Precision Therapy in Refractory Tumor
• Uses: Oxazolidine derivatives with potential antitumor activity.

Technology Process of Oxazolidine

There total 9 articles about Oxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 1,3-oxazolidine (504-76-7)

Guidance literature:

Reference yield: 92.0%

→ 1,3-oxazolidine (504-76-7) + Phenylephrin (59-42-7)

Guidance literature:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethanolamine (141-43-5) → 1,3-oxazolidine (504-76-7)

Guidance literature:

Destillation des erhaltenen 1,3,5-Tris-<2-hydroxy-aethyl>-hexahydro-<1,3,5>triazins unter vermindertem Druck;

upstream raw materials:

1,3,5-tris(2-hydroxyethyl)-1,3,5-triazacyclohexane

formaldehyd

ethanolamine

N-(2-chloroethyl)-N'-(4-methylthiophenyl)urea

Downstream raw materials:

C₂₅H₃₀ClN₇O₄S

4-ethoxycarbonyl-5-phenyl-2-trifluoromethyl imidazole

(2S,4S,5S)-2-(3,4-Dimethyl-5-phenyloxazolidin-2-yl) phenyl lithium

3-acetyl-1,3-oxazolidine

Refernces

• 1、 Higashiya, Seiichiro,Devarajan, Thamarai Selvi,Rane-Fondacaro, Manisha V.,Dangler, Christopher,Snyder, Jeremy,Haldar, Pradeep. "Synthesis of oxygen-containing spirobipyrrolidinium salts for high conductivity room temperature ionic liquids". . p. 1600 - 1609. Retrieved 2009.
• 2、 Huang, Yuanzheng,Jia, Ying,Shen, Keke,Hou, Ruomeng,Zhang, Yongyong,Hou, Li'an. "Degradation of gaseous unsymmetrical dimethylhydrazine by vacuum ultraviolet coupled with MnO2". supporting information. p. 1194 - 1202. Retrieved 2021/02/06.