Benzene, 5-methoxy-1,3-dimethyl-2-nitro-

Base Information

• Chemical Name: Benzene, 5-methoxy-1,3-dimethyl-2-nitro-
• CAS No.: 61019-03-2
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.191
• Hs Code.: 2909309090
• Mol file: 61019-03-2.mol

Synonyms:Anisole,3,5-dimethyl-4-nitro;2,6-dimethyl-4-methoxynitrobenzene;3,5-Dimethyl-4-nitro-anisol;4-nitro-3,5-dimethylanisole;Benzene, 5-methoxy-1,3-dimethyl-2-nitro-;Benzene,5-methoxy-1,3-dimethyl-2-nitro;Methyl-(4-nitro-3.5-dimethyl-phenyl)-aether;3,5-dimethyl-4-nitro-anisole;

Chemical Property of Benzene, 5-methoxy-1,3-dimethyl-2-nitro-

Chemical Property:

• Vapor Pressure: 0.00267mmHg at 25°C
• Melting Point: 48-50 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 295.6°Cat760mmHg
• Flash Point: 135.9°C
• PSA: 55.05000
• Density: 1.148g/cm³
• LogP: 2.74340
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

5-Methoxy-1,3-dimethyl-2-nitrobenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 5-methoxy-1,3-dimethyl-2-nitro-

There total 10 articles about Benzene, 5-methoxy-1,3-dimethyl-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

3,5-dimethylmethoxybenzene (874-63-5) → 2-nitro-3,5-dimethylanisole (18102-38-0) + 5-methoxy-1,3-dimethyl-2-nitrobenzene (61019-03-2)

Guidance literature:

With nitric acid; hydrazine; at 25 ℃; Rate constant;

Reference yield: 39.5%

nitromethane (75-52-5) + 2,6-dimethyl-4-methoxypyrylium perchlorate → 5-methoxy-1,3-dimethyl-2-nitrobenzene (61019-03-2)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; for 0.75h; Heating;

DOI:10.1002/(SICI)1099-1344(200005)43:6<565::AID-JLCR342>3.0.CO;2-Q

Reference yield:

4-methoxy-2,6-dimethylbenzylaldehyde (19447-00-8) → 5-methoxy-1,3-dimethyl-2-nitrobenzene (61019-03-2)

Guidance literature:

With nitric acid; at 80 ℃; zuletzt Erwaermen auf Siedetemperatur;

DOI:10.1021/ja01213a054

upstream raw materials:

nitromethane

4-methoxy-2,6-dimethylbenzylaldehyde

3,5-dimethyl-4-nitrophenol

dimethyl sulfate

Downstream raw materials:

4-methoxy-2,6-dimethylaniline

acetic acid-(4-methoxy-2,6-dimethyl-anilide)

bis-(4-methoxy-2,6-dimethyl-phenyl)-diazene-N,N'-dioxide

2,6-dimethyl-4-methoxyaniline hydrochloride

Refernces

• 1、 Cockroft, Scott L.,Perkins, Julie,Zonta, Cristiano,Adams, Harry,Spey, Sharon E.,Low, Caroline M. R.,Vinter, Jeremy G.,Lawson, Kevin R.,Urch, Christopher J.,Hunter, Christopher A.. "Substituent effects on aromatic stacking interactions". . p. 1062 - 1080. Retrieved 2007/12/27.
• 2、 Draper, Mark R.,Ridd, John H. A.. "Nitration in Aqueous Nitric Acid: the Rate Profile and the Limiting Reaction Rates". . p. 94 - 99. Retrieved 2007/10/02.