Tetrahydrofurfuryl methanesulfonate

Base Information

• Chemical Name: Tetrahydrofurfuryl methanesulfonate
• CAS No.: 72641-13-5
• Molecular Formula: C6H12 O4 S
• Molecular Weight: 180.22208
• Hs Code.: 2932190090
• NSC Number: 103198
• DSSTox Substance ID: DTXSID50295601
• Mol file: 72641-13-5.mol

Synonyms:Methanesulfonic acidtetrahydrofuran-2-ylmethyl ester;NSC 103198;Tetrahydrofurfuryl mesylate;Tetrahydrofurfuryl methanesulfonate;

Chemical Property of Tetrahydrofurfuryl methanesulfonate

Chemical Property:

• Vapor Pressure: 0.000451mmHg at 25°C
• Refractive Index: 1.465
• Boiling Point: 324.9°C at 760 mmHg
• Flash Point: 150.3°C
• PSA: 60.98000
• Density: 1.245g/cm³
• LogP: 1.22240
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 180.04563003
• Heavy Atom Count: 11
• Complexity: 203

Purity/Quality:

99% ^*data from raw suppliers

(Tetrahydrofuran-2-yl)methylmethanesulfonate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)OCC1CCCO1

Technology Process of Tetrahydrofurfuryl methanesulfonate

There total 3 articles about Tetrahydrofurfuryl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Tetrahydrofurfuryl alcohol (97-99-4) + methanesulfonyl chloride (124-63-0) → tetrahydro-2-furanmethanol methanesulfonate (ester) (72641-13-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 36h;

Reference yield:

Tetrahydrofurfuryl alcohol (97-99-4) → tetrahydro-2-furanmethanol methanesulfonate (ester) (72641-13-5)

Guidance literature:

With triethylamine; In tetrahydrofuran;

Reference yield:

Tetrahydrofurfuryl alcohol (97-99-4) + methanesulfonyl chloride (124-63-0) → tetrahydro-2-furanmethanol methanesulfonate (ester) (72641-13-5)

Guidance literature:

With pyridine; at 20 ℃; for 60h; Cooling with ice;

upstream raw materials:

Tetrahydrofurfuryl alcohol

methanesulfonyl chloride

Downstream raw materials:

quizalofop-p-tefuryl

2-(tetrahydrofuran-2-yl)acetonitrile

(1E,7Z)-1-Phenyl-8-(toluene-4-sulfinyl)-octa-1,7-dien-3-ol

(Z)-1-Phenyl-6-(toluene-4-sulfinyl)-hex-5-en-1-ol

Refernces

• 1、 Ando, Kaori,Hattori, Junichiro. "One-pot preparation of Julia-Kocienski sulfides and sulfones from alcohols". . . Retrieved 2019/08/12.
• 2、 Said, Madhukar S.,Khandare, Lina,Shinde, Sandip S.. "Molybdenum oxide-mediated facile aliphatic nucleophilic fluorination". supporting information. p. 59 - 62. Retrieved 2016/12/23.