2-(diethylamino)acetohydrazide (non-preferred name)

Base Information

• Chemical Name: 2-(diethylamino)acetohydrazide (non-preferred name)
• CAS No.: 2644-33-9
• Molecular Formula: C6H15 N3 O
• Molecular Weight: 145.205
• Mol file: 2644-33-9.mol

Synonyms:(Diethylamino)acethydrazide;(Diethylamino)acetic acid hydrazide; N,N-Diethylglycine hydrazide;N-Amino-2-(diethylamino)acetamide; [(Diethylamino)acetyl]hydrazine

Chemical Property of 2-(diethylamino)acetohydrazide (non-preferred name)

Chemical Property:

• Vapor Pressure: 0.00452mmHg at 25°C
• Boiling Point: 277.5°Cat760mmHg
• Flash Point: 121.6°C
• PSA: 61.85000
• Density: 1.005g/cm³
• LogP: 0.85870

Purity/Quality:

2-(diethylamino)acetohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(diethylamino)acetohydrazide (non-preferred name)

There total 2 articles about 2-(diethylamino)acetohydrazide (non-preferred name) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-diethylglycine methyl ester (30280-35-4) → 2-(diethylamino)acetylhydrazide (2644-33-9)

Guidance literature:

With hydrazine; In ethanol;

Reference yield:

ethyl N,N-diethylglycinate (2644-21-5) → 2-(diethylamino)acetylhydrazide (2644-33-9)

Guidance literature:

With ethanol; hydrazine hydrate;

Reference yield: 71.0%

2-(diethylamino)acetylhydrazide (2644-33-9) + (E)-N'-(1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3-yl)-N,N-dimethylformimidamide → 3-(3-((diethylamino)methyl)-4H-1,2,4-triazol-4-yl)-1-(4-methoxyphenyl)-6-(4-(2-oxopiperidin-1-yl)phenyl)-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one

Guidance literature:

With acetic acid; at 80 ℃; for 2h;

DOI:10.1016/j.bmc.2017.03.055

upstream raw materials:

ethyl N,N-diethylglycinate

N,N-diethylglycine methyl ester

Downstream raw materials:

Durolaldehyd-N,N-diethylamino-acethydrazon

2-Chlorbenzaldehyd-N,N-diethylaminoacethydrazon

4-Nitrobenzaldehyd-N,N-diethylaminoacethydrazon

3,4,5-Trimethoxybenzaldehyd-N,N-diethylamino-acethydrazon

Refernces

• 1、 -. "Methods for treating an inflammatory condition or inhibiting JNK". . . Retrieved 2008/06/13.
• 2、 EDWARDS,HAMER,STEWART. "SYNTHESIS OF ALIPHATIC AMINO-ACID HYDRAZIDES AS POTENTIAL". . p. 618 - 626. Retrieved 2007/10/05.