3-CHLOROCARBAZOLE

Base Information

• Chemical Name: 3-CHLOROCARBAZOLE
• CAS No.: 2732-25-4
• Molecular Formula: C12H8 Cl N
• Molecular Weight: 201.655
• Hs Code.: 2933990090
• Mol file: 2732-25-4.mol

Synonyms:Carbazole,3-chloro- (6CI,7CI,8CI);3-Chlorocarbazole;3-Chloro-9H-carbazole;

Chemical Property of 3-CHLOROCARBAZOLE

Chemical Property:

• Appearance/Colour: White to yellow powder
• Vapor Pressure: 6.73E-06mmHg at 25°C
• Refractive Index: 1.766
• Boiling Point: 388.7°Cat760mmHg
• Flash Point: 220.9°C
• PSA: 15.79000
• Density: 1.363g/cm³
• LogP: 3.97450

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-CHLORO-9H-CARBAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Chloro-9H-carbazole is a standard for environmental testing and research. An aryl hydrocarbon receptor agonist. Substance for the characterization and biological potency of mono- to tetra-halogenated carbazoles.

Technology Process of 3-CHLOROCARBAZOLE

There total 5 articles about 3-CHLOROCARBAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

dichloromethane (75-09-2) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1) → N-methylcarbazole (1484-12-4) + 3-chloro-9H-carbazole (2732-25-4) + N-ethylcarbazole (86-28-2) + di(9H-carbazol-9-yl)methane (6510-63-0)

Guidance literature:

In dichloromethane; for 18h; Irradiation;

DOI:10.1016/S0040-4039(01)91284-5

Reference yield: 35.0%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) → N-methylcarbazole (1484-12-4) + 3-chloro-9H-carbazole (2732-25-4) + N-ethylcarbazole (86-28-2) + di(9H-carbazol-9-yl)methane (6510-63-0)

Guidance literature:

In dichloromethane; for 18h; Irradiation;

DOI:10.1016/S0040-4039(01)91284-5

Reference yield: 12.0%

N-(N-4-chlorophenyl-N-phenylamino)phthalimide (262606-99-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 3-chloro-9H-carbazole (2732-25-4) + N-(4-chlorophenyl)-[1,1'-biphenyl]-4-amine

Guidance literature:

With aluminium trichloride; at 20 ℃; for 6h;

DOI:10.1021/jo016124r

upstream raw materials:

dichloromethane

9H-carbazole

N-chlorocarbazole

N-(N-4-chlorophenyl-N-phenylamino)phthalimide

Downstream raw materials:

3-chloro-N-acetylcarbazole

3-chloro-6-nitro-9H-carbazole

3-([1,1'-biphenyl]-4-yl)-9H-carbazole

9H-carbazole

Refernces

• 1、 Kikugawa,Aoki,Sakamoto. "Synthesis of carbazoles from N-(N,N-diarylamino)phthalimides with aluminum chloride via diarylnitrenium ions". . p. 8612 - 8615. Retrieved 2007/10/03.
• 2、 Balsells, R. Erra,Frasca, A. R.. "PHOTOCHEMICAL REACTION OF CARBAZOLE AND SOME DERIVATIVES IN DICHLOROMETHANE". . p. 5363 - 5366. Retrieved 2007/10/02.