2-[(2,4-DICHLOROPHENOXY)METHYL]OXIRANE

Base Information

• Chemical Name: 2-[(2,4-DICHLOROPHENOXY)METHYL]OXIRANE
• CAS No.: 2212-07-9
• Molecular Formula: C9H8Cl2O2
• Molecular Weight: 219.067
• Hs Code.: 2910900090
• Mol file: 2212-07-9.mol

Synonyms:Oxirane,[(2,4-dichlorophenoxy)methyl]- (9CI);Propane,1-(2,4-dichlorophenoxy)-2,3-epoxy- (7CI,8CI);1-(2,4-Dichlorophenoxy)-2,3-epoxypropane;2,4-Dichlorophenoxymethyloxirane;2,4-Dichlorophenyl glycidyl ether;2-[(2,4-Dichlorophenoxy)methyl]oxirane;NSC 634;NSC 71442;

Chemical Property of 2-[(2,4-DICHLOROPHENOXY)METHYL]OXIRANE

Chemical Property:

• Vapor Pressure: 0.00148mmHg at 25°C
• Refractive Index: 1.567
• Boiling Point: 305.5 °C at 760 mmHg
• Flash Point: 124.3 °C
• PSA: 21.76000
• Density: 1.389 g/cm³
• LogP: 2.77100

Purity/Quality:

99%, ^*data from raw suppliers

2-[(2,4-DICHLOROPHENOXY)METHYL]OXIRANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(2,4-DICHLOROPHENOXY)METHYL]OXIRANE

There total 4 articles about 2-[(2,4-DICHLOROPHENOXY)METHYL]OXIRANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,4-dichlorophenol (120-83-2,40477-79-0) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1-(2,4-dichloro-phenoxy)-2,3-epoxypropane (2212-07-9)

Guidance literature:

With n-Bu₄NOSO₂OCH₂CHOHCH₃; potassium carbonate; at 75 - 80 ℃; for 1.5h;

DOI:10.1080/00397919408011305

Reference yield:

2,4-dichlorophenol (120-83-2,40477-79-0) → 1-(2,4-dichloro-phenoxy)-2,3-epoxypropane (2212-07-9)

Guidance literature:

With potassium carbonate; mercury; In epichlorohydrin;

Reference yield:

2,4-dichlorophenol (120-83-2,40477-79-0) + 1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) → 1-(2,4-dichloro-phenoxy)-2,3-epoxypropane (2212-07-9)

Guidance literature:

With potassium carbonate; In acetonitrile; Reflux;

DOI:10.3184/174751916X14538054606043

upstream raw materials:

2,4-dichlorophenol

epichlorohydrin

1,2-Epoxy-3-bromopropane

Downstream raw materials:

1-[butyl-(2-morpholin-4-yl-ethyl)-amino]-3-(2,4-dichloro-phenoxy)-propan-2-ol

3-(2',4'-dichlorophenoxy)-1-(n-heptylthio)-2-propanol

1-azido-3-(2,4-dichlorophenyl)propan-2-ol

1-(2,4-dichloro-phenoxy)-propan-2-ol

Refernces

• 1、 -. "Substituted diaryl compound and preparation method and application thereof". Paragraph 0073-0075; 0076. . Retrieved 2021/09/15.
• 2、 Liu,Chen,Cao,Li. "A novel method for synthesis of aryl glycidyl ethers". . p. 833 - 838. Retrieved 2007/10/02.