Furfurylidenemalononitrile

Base Information

• Chemical Name: Furfurylidenemalononitrile
• CAS No.: 3237-22-7
• Molecular Formula: C8H4 N2 O
• Molecular Weight: 144.133
• Hs Code.: 29321900
• European Community (EC) Number: 623-628-2
• NSC Number: 1333
• UNII: L7FT4U2XXU
• DSSTox Substance ID: DTXSID90186084
• Nikkaji Number: J150.470C
• ChEMBL ID: CHEMBL300341
• Mol file: 3237-22-7.mol

Synonyms:3237-22-7;Furfurylidenemalononitrile;(2-Furanylmethylene)malononitrile;2-(Furan-2-ylmethylene)malononitrile;2-(furan-2-ylmethylidene)propanedinitrile;MALONONITRILE, FURFURYLIDENE-;Furfural-malonitril;2-Furfurylidenemalononitrile;1,1-Dicyano-2-(2-furyl)ethylene;Furfural-malonitril [German];RGW 904;NSC 1333;F 2375;L7FT4U2XXU;Propanedinitrile, (2-furanylmethylene)-;NSC-1333;(furan-2-ylmethylidene)propanedinitrile;2-(2-Furylmethylene)malononitrile;Tyrphostin deriv. 8;UNII-L7FT4U2XXU;1.1-dicyano-2-furylethene;BDBM4278;CHEMBL300341;SCHEMBL3006584;DTXSID90186084;NSC1333;RGW-904;2-(2-furylmethylidene)malononitrile;(2-Furanylmethylene)propanedinitrile;2-(2-Furylmethylene)malononitrile #;BBL025714;MFCD00137623;STL377839;AKOS000406017;2-(2-Furanylmethylene)propanedinitrile;LS-88943;2-(furan-2-yl-methylene)-propanedinitrile;Propanedinitrile, 2-(2-furanylmethylene)-;2-[(furan-2-yl)methylidene]propanedinitrile;CS-0320392;FT-0604626;7K-021;F-2375;J-018718

Chemical Property of Furfurylidenemalononitrile

Chemical Property:

• Vapor Pressure: 0.0096mmHg at 25°C
• Melting Point: 70-74 °C(lit.)
• Boiling Point: 264.6°Cat760mmHg
• Flash Point: 113.8°C
• PSA: 60.72000
• Density: 1.239g/cm³
• LogP: 1.71016
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 144.032362755
• Heavy Atom Count: 11
• Complexity: 244

Purity/Quality:

99% ^*data from raw suppliers

2-(2-furylmethylene)malononitrile ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)C=C(C#N)C#N

Technology Process of Furfurylidenemalononitrile

There total 8 articles about Furfurylidenemalononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-(2-furylmethylene)-p-chloraniline (13533-22-7) + malononitrile (109-77-3) → 2-cyano-3-(2-furanyl)acrylonitrile (3237-22-7) + 4-chloro-aniline (106-47-8)

Guidance literature:

With sodium dodecyl-sulfate; In water; at 25 - 30 ℃; for 0.25h;

Reference yield: 84.0%

C11H8BrNO2 (1062320-38-0) + malononitrile (109-77-3) → m-bromophenylhydroxylamine (24171-78-6) + 2-cyano-3-(2-furanyl)acrylonitrile (3237-22-7)

Guidance literature:

With sodium dodecyl-sulfate; In water; at 25 - 30 ℃; for 0.333333h;

Reference yield:

2-furfurylidenecyanothioacetamide (39145-34-1) → 2-cyano-3-(2-furanyl)acrylonitrile (3237-22-7) + C18H18N4O2S + (E)-3-Furan-2-yl-2-(4-methyl-5-phenylazo-thiazol-2-yl)-acrylonitrile

Guidance literature:

With sodium hydroxide; 1-(N-phenylhydrazono)-1-chloropropanone; In ethanol; Ambient temperature;

DOI:10.1080/10426509808032458

upstream raw materials:

2-furfurylidenecyanothioacetamide

1-(N-phenylhydrazono)-1-chloropropanone

2-(2-phenylhydrazono)-2-chloro-1-phenylethanone

C₁₁H₈BrNO₂

Downstream raw materials:

2-amino-4-(2-furyl)-7,7-dimethyl-5-oxo-1-phenyl-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile

Refernces

• 1、 Zohdi, Hussein F.,Rateb, Nora M.,Abdelhamid, Abdou O.. "Reactions with hydrazonoyl halides XIX1: Synthesis of some pyrazole and 5-arylazothiazole derivatives". . p. 103 - 117. Retrieved 2007/10/03.