3α,4α-Diphenylcyclobutane-1β,2α-dicarboxylic acid bis[(1R,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester

Base Information

• Chemical Name: 3α,4α-Diphenylcyclobutane-1β,2α-dicarboxylic acid bis[(1R,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester
• CAS No.: 113297-77-1
• Molecular Formula: C₃₈H₄₆N₂O₈
• Molecular Weight: 658.792
• Mol file: 113297-77-1.mol

Synonyms:1,2-Cyclobutanedicarboxylicacid, 3,4-diphenyl-,bis[2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester,stereoisomer; w-Truxilline

Chemical Property of 3α,4α-Diphenylcyclobutane-1β,2α-dicarboxylic acid bis[(1R,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 111.68000
• Density: 1.29g/cm³
• LogP: 3.81080

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3α,4α-Diphenylcyclobutane-1β,2α-dicarboxylic acid bis[(1R,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester

There total 1 articles about 3α,4α-Diphenylcyclobutane-1β,2α-dicarboxylic acid bis[(1R,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) → 3,4-diphenyl-cyclobutane-1,2-dicarboxylic acid bis-(2-methoxycarbonyl-tropan-3-yl ester),β-truxinic acid bis-(2-methoxycarbonyl-tropyl ester) (490-15-3,113297-77-1,113350-52-0,113350-54-2,113350-57-5,113350-58-6)

Guidance literature:

With hydrogenchloride;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + 3,4-diphenyl-cyclobutane-1,2-dicarboxylic acid bis-(2-methoxycarbonyl-tropan-3-yl ester),β-truxinic acid bis-(2-methoxycarbonyl-tropyl ester) (490-15-3,113297-77-1,113350-52-0,113350-54-2,113350-57-5,113350-58-6) → methylene chloride (74-87-3) + β-truxinic acid (528-34-7,898816-27-8) + ecgonine (481-37-8)

Guidance literature:

upstream raw materials:

methanol

Downstream raw materials:

methylene chloride

β-truxinic acid

ecgonine