5alpha-Androstane-3beta,7alpha,17beta-triol

Base Information

• Chemical Name: 5alpha-Androstane-3beta,7alpha,17beta-triol
• CAS No.: 19316-62-2
• Molecular Formula: C19H32 O3
• Molecular Weight: 308.461
• UNII: 7269TBU72V
• DSSTox Substance ID: DTXSID80940990
• Nikkaji Number: J573.367G
• Wikidata: Q27158738
• Mol file: 19316-62-2.mol

Synonyms:3 beta,7 alpha,17 beta-trihydroxy-5 alpha-androstane;5 alpha-androstane-3 beta,7 alpha,17 beta-triol;androstane-3,7,17-triol;androstane-3,7,17-triol, (3alpha,5alpha,7alpha,17beta)-isomer;androstane-3,7,17-triol, (3alpha,5alpha,7beta,17beta)-isomer

Chemical Property of 5alpha-Androstane-3beta,7alpha,17beta-triol

Chemical Property:

• Vapor Pressure: 3.08E-10mmHg at 25°C
• Boiling Point: 456.1°Cat760mmHg
• Flash Point: 207.4°C
• PSA: 60.69000
• Density: 1.163g/cm³
• LogP: 2.72170
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 308.23514488
• Heavy Atom Count: 22
• Complexity: 452

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2O)C(CC4C3(CCC(C4)O)C)O
• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](C[C@@H]4[C@@]3(CC[C@@H](C4)O)C)O

Technology Process of 5alpha-Androstane-3beta,7alpha,17beta-triol

There total 4 articles about 5alpha-Androstane-3beta,7alpha,17beta-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-androgen-3,17-diol (571-20-0) → Epiandrosterone (481-29-8) + 5-alpha-Androstane-3-beta,7-alpha,17-beta-triol (19316-62-2) + Stanolone (521-18-6) + Androstenedione (63-05-8) + androstanedione (846-46-8) + 5α-androstane-3β,6α,17β-triol (49644-04-4)

Guidance literature:

With oxygen; at 37 ℃; Kinetics; metabolism by canine (beagle) prostatic slices, medium 199, T-labelled, var. temp., cofactor requirements, subcellular distribution, effects of castration;

DOI:10.1016/0039-128X(80)90099-9

Reference yield:

→ 5α-Androstan-3β,7α,17β-triol (19316-58-6,19316-62-2,41843-62-3,47189-68-4,49644-03-3,54382-65-9,55448-82-3,55448-83-4)

Guidance literature:

entspr. 'Androstandion', NaBH4;

DOI:10.1016/0039-128X(79)90114-4

Reference yield:

→ 5α-Androstan-3β,7β,17β-triol (19316-58-6,19316-62-2,41843-62-3,47189-68-4,49644-03-3,54382-65-9,55448-82-3,55448-83-4)

Guidance literature:

entspr. 'Androstandion', NaBH4;

DOI:10.1016/0039-128X(79)90114-4

upstream raw materials:

5-androgen-3,17-diol

Refernces

• 1、 Bell,Jones,Meakins,Miners,Wilkins. "Microbiological hydroxylation. Part XX. Hydroxylation of dioxygenated 5alpha-androstanes with the fungi Absidia regnieri and Syncephelastrum racemosum.". . p. 2040 - 2043. Retrieved 2007/10/10.