alpha-Tomatine

Base Information Edit

Chemical Name:alpha-Tomatine
CAS No.:17406-45-0
Molecular Formula:C50H83NO21
Molecular Weight:1034.2
Hs Code.:29329990
European Community (EC) Number:241-429-5
NSC Number:234440,9223
Wikipedia:Tomatine
Wikidata:Q105234914
Mol file:17406-45-0.mol

Synonyms:17406-45-0;Tomatine [for Cholesterol assay];.alpha.-Tomatine;NSC9223;a-tomatine;NSC-9223;alpha -tomatine;C50-H83-N-O21;NSC-234440;.beta.-D-Galactopyranoside,5.alpha.,22.beta.,25S)-spirosolan-3-yl O-.beta.-D-glucopyranosyl-(1.fwdarw.2)-O-[.beta.-D-xylopyranosyl-(1.fwdarw.3)]-O-.beta.-D-glucopyranosyl-(1.fwdarw.4)-;SCHEMBL23567817;.beta.-D-Galactopyranoside, (3.beta.,5.alpha.,22.beta.,25S)-spirosolan-3-yl O-.beta.-D-glucopyranosyl-(1.fwdarw.2)-O-[.beta.-D-xylopyranosyl-(1.fwdarw.3)]-O-.beta.-D-glucopyranosyl-(1.fwdarw.4)-;.beta.-D-Galactopyranoside, (3.beta.,5.alpha.,22.beta.,25S)-spirosolan-3-yl O-.beta.-D-glucopyranosyl-(1?2)-O-[.beta.-D-xylopyranosyl-(1?3)]-O-.beta.-D-glucopyranosyl-(1?4)-;CC12CCC3C(CCC4CC(CCC34C)OC5OC(CO)C(OC6OC(CO)C(O)C(OC7OCC(O)C(O)C7O)C6OC8OC(CO)C(O)C(O)C8O)C(O)C5O)C2CC9OC%10(CCC(C)CN%10)C(C)C19;NSC234440;Solasodine base + 2H, O-Hex-Hex-Hex-Pen;FT-0775470

Suppliers and Price of alpha-Tomatine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tomatine
10mg
$ 490.00

Usbiological
Tomatine
25mg
$ 355.00

TRC
Tomatine(85%)
5mg
$ 150.00

TCI Chemical
Tomatine from Tomato >80.0%(HPLC)
100mg
$ 189.00

Medical Isotopes, Inc.
Tomatine(85%)
50 mg
$ 610.00

ChemScene
Tomatine 99.38%
5mg
$ 119.00

ChemScene
Tomatine 99.38%
10mg
$ 202.00

ChemScene
Tomatine 99.38%
20mg
$ 343.00

Chem-Impex
TomatinefromTomato,98%(HPLC) 98%(HPLC)
250MG
$ 425.60

Chem-Impex
TomatinefromTomato,≥98%(HPLC) ≥98%(HPLC)
100MG
$ 186.37

Total 71 raw suppliers

Chemical Property of alpha-Tomatine Edit

Chemical Property:

Appearance/Colour:white to light yellow
Melting Point:300-305 °C
Refractive Index:1.638
Boiling Point:806.69°C (rough estimate)
PKA:12.77±0.70(Predicted)
PSA：337.86000
Density:1.48 g/cm³
LogP:-2.36850
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly)
XLogP3:-0.7
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:22
Rotatable Bond Count:11
Exact Mass:1033.54575866
Heavy Atom Count:72
Complexity:1840

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tomatine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 23/25-22
Safety Statements: 45-24/25-22

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Biological Agents -> Plant Toxins
Canonical SMILES:CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)O)OC9C(C(C(CO9)O)O)O)OC2C(C(C(C(O2)CO)O)O)O)O)O)C)C)C)NC1
Description This glycosidic alkaloid has been obtained from the dried leaves of Lycopersicum pimpinelli/olium (Syn. Solanum racemigerum) and also occurs in L. esculentum; L. hirsutum; L. peruvianum; L. peruvianum var. chutatum and L. putatum. The alkaloid forms colourless needles from MeOH and has a somewhat indefinite melting point about 270°C. It is laevorotatory with [α]20D - 30° (pyridine) and on hydrolysis with H2S04 yields tomatidine, I mole of galactose, 2 moles of glucose and 1 mole of xylose. The tetrasaccharide unit is known as lycotetraose. Partial hydrolysis with acid yields a series of products depending upon which, and how many, of the sugar residues are split off from the molecule. Those which have been isolated are: tomatidine lycotriose I (galactose-glucose-glucose); tomatidine lycotriose II (galactose-glucose-xylose); tomatidine lycobiose (galactose-glucose) and tomatidine-galactose.
Uses Precipitating agent for steroids. Tomatine is used as an antiproliferatice agent used in the suppression of breast adenocarcinoma cells.

Technology Process of alpha-Tomatine

There total 1 articles about alpha-Tomatine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: