2,3-Dibromobutane

Base Information

• Chemical Name: 2,3-Dibromobutane
• CAS No.: 5408-86-6
• Molecular Formula: C4H8 Br2
• Molecular Weight: 215.916
• Hs Code.: 2903399090
• European Community (EC) Number: 226-476-1
• NSC Number: 115796,245048,8414
• DSSTox Substance ID: DTXSID70871128
• Nikkaji Number: J1.835J
• Mol file: 5408-86-6.mol

Synonyms:2,3-dibromobutane

Chemical Property of 2,3-Dibromobutane

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 3.02mmHg at 25°C
• Melting Point: -24°C
• Refractive Index: n20/D 1.5126(lit.)
• Boiling Point: 103-108 °C160 mm Hg(lit.)
• Flash Point: 33 °C
• PSA: 0.00000
• Density: 1.756 g/mL at 25 °C(lit.)
• LogP: 2.55320
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 215.89723
• Heavy Atom Count: 6
• Complexity: 30.5

Purity/Quality:

98% ^*data from raw suppliers

2,3-Dibromobutane >99.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Halogenated Aliphatics, Saturated
• Canonical SMILES: CC(C(C)Br)Br

Technology Process of 2,3-Dibromobutane

There total 80 articles about 2,3-Dibromobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

threo-2-bromo-3-chlorobutane (19246-45-8,19246-46-9,19773-36-5,19773-37-6,19773-43-4,49623-64-5,49623-65-6,49623-66-7) → 2,3-dibromobutane (5408-86-6)

Guidance literature:

With hydrogen bromide; ferric(III) bromide; In dichloromethane; at 25 ℃; for 1h;

DOI:10.1039/c39870001013

Reference yield: 46.0%

2,3-dichlorobutane (7581-97-7) → 2,3-dibromobutane (5408-86-6) + s-butyl bromide (78-76-2,5787-31-5)

Guidance literature:

With hydrogen bromide; ferric(III) bromide; In dichloromethane; at 25 ℃; for 1h;

DOI:10.1039/c39870001013

Reference yield: 45.7%

s-butyl bromide (78-76-2,5787-31-5) → 2,3-dibromobutane (5408-86-6) + meso-2,3-dibromo-butane (5780-13-2) + 2,2-dibromobutane (50341-35-0) + 1,2,2-tribromo-1-methylpropane (62127-47-3)

Guidance literature:

With bromine; at 30 ℃; Irradiation;

upstream raw materials:

1-bromo-butane

(E/Z)-crotyl bromide

3-bromo-1-butene

butene-2

Downstream raw materials:

2,3-bis-benzenesulfonyl-butane

but-1-yne

dimethylacetylene

butene-2

Refernces

• 1、 McKean, D. C.,MacKenzie, M. W.,Morrisson, A. R.,Lavalley,J. C.,Janin, A.,et al.. "Vibrational spectra of cis and trans but-2-enes: assignments, isolated CH stretching frequencies and CH bond lengtsh". . p. 435 - 450. Retrieved 1985.
• 2、 Prince,Bremer. "". . p. 1655. Retrieved 1967.
• 3、 Garst et al.. "". . p. 5242,5245. Retrieved 1975.
• 4、 Chretien, Jacques R.,Coudert, Jean-Daniel,Ruasse, Marie-Francoise. "Solvation and Steric Effects on Electrophilic Reactivity of Ethylenic Compounds. 3. Stereo-, Regio-, and Chemoselectivity of Alkene Bromination in Methanol". . p. 1917 - 1921. Retrieved 2007/10/02.
• 5、 Yoon, K. B.,Kochi, J. K.. "Efficient Conversion of Alkyl Chlorides into Bromides". . p. 1013 - 1014. Retrieved 2007/10/02.